ArticleEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2024
Frozen elephant trunk technique using hybrid grafts: 15-year outcomes from a single-centre experience.
Article in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Incidence and Outcomes of Intraluminal Frozen Elephant Trunk Stent Graft Thrombosis After Aortic Arch Surgery: Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2026Pooled it
- Hemiarch repair versus total-arch repair with frozen elephant trunk for acute type A aortic dissection: A propensity score-matched study.JTCVS open · 2026Article
- Standardized total arch replacement using the frozen elephant trunk technique.Annals of cardiothoracic surgery · 2026Article
- Innominate artery reimplantation as a strategic step in lifetime aortic management: a vascular surgeon's perspective.Annals of cardiothoracic surgery · 2026Review
- Aortic arch replacement with descending thoracic aorta stenting for chronic dissection: early outcomes.Journal of cardiothoracic surgery · 2026Article
- Zone 1 total arch replacement with frozen elephant trunk for type A dissection: early-to-mid-term outcomes.Journal of cardiothoracic surgery · 2026Observational
- Contemporary Management of the Aortic Arch: A Narrative Review.Journal of clinical medicine · 2026Review
- Frozen elephant trunk for acute type A aortic dissection: long-term outcomes over two decades.European heart journal · 2026Article
- Total Aortic Arch Replacement With the Frozen Elephant Trunk Technique: Influence of Aortic Arch Anomalies.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Frozen elephant trunk: a narrative review of global and temporal trends.Journal of thoracic disease · 2026Review
- Sex differences in outcomes of a two-stage approach to aortic arch surgery: 8-year experience of a national aortovascular centre.Journal of cardiothoracic surgery · 2026Article
- Procedure duration and early postoperative stroke after endovascular and hybrid aortic arch reconstruction for acute aortic syndrome: a single-center retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Design, benefits, and use of a hybrid aortic arch stent graft.JTCVS open · 2025Article
- Early and 3-Year Outcomes of Frozen Elephant Trunk Procedure with Evolving E-vita Hybrid Grafts: A Retrospective Single-Centre Cohort Study over 11 Years.Journal of cardiovascular development and disease · 2025Article
- Thoracic aortic aneurysm.Nature reviews. Disease primers · 2025Review
- Commercial hybrid graft versus traditional arch replacement with frozen elephant trunk: A multi-institutional comparison.JTCVS open · 2025Article
- Advances in aortic surgery.The British journal of cardiology · 2025Article
- Hybrid Aortic Arch Replacement with Frozen Elephant Trunk (FET) Technique: Surgical Considerations, Pearls, and Pitfalls.Journal of clinical medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe purpose of the study is to compare the short- and long-term outcomes of the frozen elephant trunk (FET) technique based on 2 different hybrid grafts implanted from January 2007 to July 2022.
methodsThe study includes patients who underwent an elective or emergency FET procedure. Short-term, long-term mortality and freedom from thoracic endovascular aortic repair (TEVAR) were the primary end points. Analyses were carried out separately for the periods 2007-2012 and 2013-2022.
resultsOf the 367 enrolled, 49.3% received E-Vita Open implantation and 50.7% received Thoraflex Hybrid implants. Overall mean age was 61 years [standard deviation (SD) = 11] and 80.7% were male. The average annual volume of FET procedures was 22.7 cases/year. Compared to E-Vita Open, patients implanted with Thoraflex Hybrid grafts were more likely to receive distal anastomosis in zone 2 (68.3% vs 11.6%, P < 0.001) with a shorter stent portion, mean = 103mm (SD = 11.3) vs mean = 149 mm (SD = 12.7; P < 0.001) and they underwent a reduced visceral ischaemia time, mean = 42.5 (SD = 14.2) vs mean= 61.0 (SD = 20.2) min, P < 0.001. In the period 2013-2022, overall survival at 1, 2 and 5 years was 74.8%, 72.5% and 63.2% for Thoraflex and 73.2%, 70.7% and 64.1% for E-Vita, without significant differences between groups (log-rank test = 0.01, P = 0.907). Overall freedom from TEVAR at 1, 2 and 5 years was 66.7%, 57.6% and 39.3% for Thoraflex and 79%, 69.7% and 66% for E-Vita, with significant differences between groups (log-rank test = 5.28, P = 0.029). In a competing risk analysis adjusted for chronic/residual aortic syndromes and stent diameter, the Thoraflex group was more likely to receive TEVAR during follow-up (subdistribution hazard ratio SHR = 2.12, 95% confidence interval 1.06-4.22).
conclusionsThe FET technique addresses acute and chronic arch disease with acceptable morbidity and mortality. Downstream endovascular reinterventions are very common during follow-up.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.