Evidence map›Paper›PMID 37929938›Full record

ArticleeLife2023

Structural basis for kinase inhibition in the tripartite

René L Bærentsen, Stine V Nielsen, Ragnhild B Skjerning, Jeppe Lyngsø, Francesco Bisiak, Jan Skov Pedersen, Kenn Gerdes, Michael A Sørensen, Ditlev E Brodersen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Validation of electron-microscopy maps using solution small-angle X-ray scattering.Acta crystallographica. Section D, Structural biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

René L Bærentsen *Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-6460-4845
Stine V Nielsen *Department of Biology, University of Copenhagen, Copenhagen, Denmark.
Ragnhild B SkjerningDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.ORCID 0000-0003-3886-8086
Jeppe LyngsøDepartment of Chemistry and Interdisciplinary Nanoscience Centre (iNANO), Aarhus, Denmark.ORCID 0000-0002-6301-1300
Francesco BisiakDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-5375-6264
Jan Skov PedersenDepartment of Chemistry and Interdisciplinary Nanoscience Centre (iNANO), Aarhus, Denmark.
Kenn GerdesVoldmestergade, Copenhagen, Denmark.
Michael A SørensenDepartment of Biology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-8931-2999
Ditlev E BrodersenDepartment of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-5413-4667
Aarhus University · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many bacteria encode multiple toxin-antitoxin (TA) systems targeting separate, but closely related, cellular functions. The toxin of the

Indexed as

AntitoxinsEscherichia coli ProteinsToxin-Antitoxin SystemsEscherichia coliPhosphorylationAntitoxinsEscherichia coli ProteinsE. coliHipBAinfectious diseasemicrobiologymolecular biophysicsSer/Thr kinaseSTKstructural biologytRNA synthetaseTrpS

Identifiers

PMID37929938
PMCPMC10627512
OpenAlexW4386326280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.