Evidence map›Paper›PMID 37929833›Full record

ArticleChemical communications (Cambridge, England)2023

Chemical remodeling of the mycomembrane with chain-truncated lipids sensitizes mycobacteria to rifampicin.

Ishani V Gaidhane, Kyle J Biegas, Helen E Erickson, Prachi Agarwal, Yashpal S Chhonker, Donald R Ronning, Benjamin M Swarts

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical communications (Cambridge, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trehalose dimycolate inhibits phagosome maturation and promotes intracellularProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ishani V GaidhaneDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, MI, USA. ben.swarts@cmich.edu.
Kyle J BiegasDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, MI, USA. ben.swarts@cmich.edu.
Helen E EricksonDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE, USA.
Prachi AgarwalDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE, USA.
Yashpal S ChhonkerClinical Pharmacology Laboratory, Department of Pharmacy Practice and Science, University of Nebraska Medical Center, Omaha, NE, USA.
Donald R RonningDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE, USA.ORCID http://orcid.org/0000-0003-2583-8849
Benjamin M SwartsDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, MI, USA. ben.swarts@cmich.edu.ORCID http://orcid.org/0000-0001-8402-359X
Central Michigan University · USNebraska Medical Center · USUniversity of Nebraska Medical Center · US

Funding

Understanding trehalose synthesis and utilization in mycobacteriaR01AI105084 · NIAID · UNIVERSITY OF TOLEDO · PI RONNING, DONALD R, SUCHECK, STEVEN · 2013 to 2022
$3.7M
Chemoenzymatic synthesis of trehalose analogues as tools for investigating mycobacteriaR15AI117670 · NIAID · CENTRAL MICHIGAN UNIVERSITY · PI SWARTS, BENJAMIN MICHAEL, WOODRUFF, PETER J · 2015 to 2024
$1.3M
NIAID NIH HHS R01 AI105084NIAID NIH HHS R15 AI117670
6 · The paper itself

Abstract

The outer mycomembrane of

Indexed as

Mycobacterium tuberculosisRifampinCell MembraneCell WallLipidsLipidsRifampin

Identifiers

PMID37929833
PMCPMC10872977
OpenAlexW4388093920

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.