Evidence map›Paper›PMID 37929734›Full record

ArticleEndocrine, metabolic & immune disorders drug targets2024

Accuracy of Fasting Blood Glucose and Body Mass Index in Predicting Gestational Diabetes Mellitus in China.

Jing-Ru Jiao, Ya-Na Gao, Ling-Chao Wang, Jing Wang, Wei-Jing Jia, Hui-Ling Xue, Rui Li, Hong-Li Wu, Mei-Mei Wang

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Article in Endocrine, metabolic & immune disorders drug targets, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

Jing-Ru JiaoDepartment of Obstetrics and Gynecology, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, China.
Ya-Na GaoDepartment of Obstetrics and Gynecology, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, China.
Ling-Chao Wang66350 Medical Company of PLA, Baoding, 071000, Hebei, China.
Jing WangDepartment of Obstetrics and Gynecology, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, China.
Wei-Jing JiaDepartment of Obstetrics and Gynecology, Xiong County Hospital of Xiongan New District, Baoding, 071000, Hebei, China.
Hui-Ling XueDepartment of Obstetrics and Gynecology, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, China.
Rui LiDepartment of Obstetrics and Gynecology, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, China.
Hong-Li WuDepartment of Obstetrics and Gynecology, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, China.
Mei-Mei WangDepartment of Obstetrics and Gynecology, Baoding No.1 Hospital of TCM, Baoding, 071000, Hebei, China.

Funding

Baoding Science and Technology Plan Project 2241ZF120, 2341ZF162Hebei University Medical Discipline Cultivation Project 2023B04Hospital fund project of Affiliated Hospital of Hebei University 2022QC66Scientific Research Department of Affiliated Hospital of Hebei University 2016Q016Youth Science and Technology Project From Health Commission of Hebei Province 20170827
6 · The paper itself

Abstract

backgroundResearch suggests that lowering maternal morbidities associated with gestational diabetes mellitus (GDM) can be achieved with earlier risk group identification.

aimsTherefore, the purpose of this study was to examine potential markers for identifying first-trimester pregnant women who are at high risk for developing GDM.

methodsThis was a retrospective cohort study. The pertinent maternal clinical data were retrieved prior to 13+6 weeks of gestation, and a binary logistic regression analysis was used to identify potential GDM predictors. The predictive accuracy was evaluated using the area below the receiver operating characteristics curves.

resultsIn comparison to the control group, the GDM group had significantly higher mean values for age, body mass index (BMI), mean fasting blood glucose (FBG), and hemoglobin (p < 0.05). The Pearson's correlation coefficients indicated that the first-trimester FBG was significantly positively correlated with the second-trimester FBG. Higher FBG and BMI values were associated with an increased risk of developing GDM (odds ratio (OR) = 3.04, 95% confidence interval [CI] = 2.03-4.55 and OR = 1.18, 95% CI = 1.12-1.25). In terms of predicting GDM, the FBG parameter demonstrated the greatest area under the curve values (0.66), followed by the BMI parameter (0.69). For GDM prediction, the cut-off value for FBG was 4.32 mM, whereas that for BMI was 23.7 kg/m

conclusionThe first-trimester FBG and BMI could be utilized to predict gestational diabetes.

Indexed as

Blood GlucoseBody Mass IndexDiabetes, GestationalFastingPredictive Value of TestsAdultBiomarkersChinaFemaleHumansPregnancyPregnancy Trimester, FirstRetrospective StudiesRisk FactorsBiomarkersBlood GlucoseBMI parameter.Body mass indexfasting blood glucosegestational diabetes mellitushemoglobinprediction

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PMID37929734

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.