Evidence map›Paper›PMID 37929507›Full record

ReviewMedical gas research

Therapeutic effect of hydrogen and its mechanisms in kidney disease treatment.

Jin Cheng, Minmin Shi, Xuejun Sun, Hongtao Lu

Open access · hybridAbstract readReview
In one paragraph

Review in Medical gas research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jin ChengNaval Medical Center, Naval Medical University, Shanghai, China.
Minmin ShiNaval Medical Center, Naval Medical University, Shanghai, China.
Xuejun SunDepartment of Naval Medicine, Naval Medical University; Center of Hydrogen Science, Shanghai Jiao Tong University, Shanghai, China.
Hongtao LuDepartment of Naval Medicine, Naval Medical University, Shanghai, China.
Shanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogen is a simple, colorless, and biologically active small molecule gas that can react with reactive oxygen species. Recent research suggests that hydrogen possesses several biological effects, including antioxidant, anti-inflammatory, and anti-apoptotic effects, while exhibiting an extremely high level of safety. Hydrogen application has shown promise in treating a range of acute and chronic diseases, both benign and malignant. Importantly, an increasing number of clinical studies on hydrogen have demonstrated its efficacy and safety in treating various diseases. This review highlights the beneficial effects of hydrogen in kidney diseases, summarizes potential mechanisms by which hydrogen may act in these diseases, and proposes several promising avenues for future research.

Indexed as

Hydrogen SulfideKidney DiseasesAntioxidantsHumansHydrogenReactive Oxygen SpeciesAntioxidantsHydrogenHydrogen SulfideReactive Oxygen Speciesacute kidney injuryanti-apoptosisanti-inflammationanti-oxidationchronic kidney diseaseend-stage renal diseasehydrogentherapeutic effect

Identifiers

PMID37929507
PMCPMC10715323
OpenAlexW4380876724

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.