Evidence map›Paper›PMID 37928556›Full record

ReviewFrontiers in immunology2023

Combinatorial blockade for cancer immunotherapy: targeting emerging immune checkpoint receptors.

Dia Roy, Cassandra Gilmour, Sachin Patnaik, Li Lily Wang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Decoding T cell exhaustion in the tumour microenvironment.Experimental & molecular medicine · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Targeted nano-drug delivery systems for tumor immunotherapy.Journal of pharmaceutical analysis · 2026
    Review
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  14. Review
  15. Article
  16. Review
  17. Unraveling the dual role of METTL3-mediated mCancer biology & therapy · 2025
    Review
  18. Article
  19. Review
  20. Emerging new immune checkpoint inhibitors in solid tumor immunotherapy.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dia RoyDepartment of Translational Hematology and Oncology Research, Cleveland Clinic Foundation, Cleveland, OH, United States.
Cassandra GilmourDepartment of Translational Hematology and Oncology Research, Cleveland Clinic Foundation, Cleveland, OH, United States.
Sachin PatnaikDepartment of Translational Hematology and Oncology Research, Cleveland Clinic Foundation, Cleveland, OH, United States.
Li Lily WangDepartment of Translational Hematology and Oncology Research, Cleveland Clinic Foundation, Cleveland, OH, United States.

Funding

VISTA, a novel checkpoint that suppresses anti-tumor T cell responsesR01CA164225 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI WANG, LI LILY · 2012 to 2023
$3.3M
Transfer Application - R01 CA223804 - Chemoimmunoprevention of EGFR-Driven Non-Small Cell Lung CancerR01CA223804 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI WANG, LI LILY, YOU, MING · 2018 to 2022
$3.3M
The Roles of a Novel Immune-Checkpoint Receptor Complex in Driving T Cell Dysfunction in CancerR21CA258618 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI WANG, LI LILY · 2022 to 2023
$409k
Dissecting the roles of a novel immune-checkpoint receptor complex in driving T cell dysfunction in cancersF31CA257276 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI GILMOUR, CASSANDRA · 2021 to 2022
$76k
NCI NIH HHS F31 CA257276NCI NIH HHS R01 CA164225NCI NIH HHS R01 CA223804NCI NIH HHS R21 CA258618
6 · The paper itself

Abstract

The differentiation, survival, and effector function of tumor-specific CD8

Indexed as

Hepatitis A Virus Cellular Receptor 2NeoplasmsHumansImmunotherapyReceptors, ImmunologicT-Lymphocytes, CytotoxicHepatitis A Virus Cellular Receptor 2Receptors, Immunologiccombinatorial immunotherapiesCTLA-4immune checkpoint inhibitorsLAG3PD-1TIGITTIM3VISTA

Identifiers

PMID37928556
PMCPMC10620683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.