Evidence map›Paper›PMID 37928470›Full record

ArticleFrontiers in medicine2023

Prevalence of diagnostically-discrepant

Farhan Anwar, Marielle Clark, Jason Lindsey, Rachel Claus-Walker, Asad Mansoor, Evy Nguyen, Justin Billy, William Lainhart, Kareem Shehab, V K Viswanathan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Journal of bacteriology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Farhan AnwarSchool of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, AZ, United States.
Marielle ClarkSchool of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, AZ, United States.
Jason LindseySchool of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, AZ, United States.
Rachel Claus-WalkerSchool of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, AZ, United States.
Asad MansoorSchool of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, AZ, United States.
Evy NguyenSchool of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, AZ, United States.
Justin BillySchool of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, AZ, United States.
William LainhartDepartment of Pathology, Clinical Microbiology Laboratories, Banner University Medical Center, Tucson, AZ, United States.
Kareem ShehabDepartment of Pediatrics, College of Medicine, University of Arizona, Tucson, AZ, United States.
V K ViswanathanSchool of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, AZ, United States.
Gayatri VedantamSchool of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, AZ, United States.
University of Arizona · USBanner - University Medical Center Tucson · USSouthern Arizona VA Health Care System · US

Funding

A Bio-controlled, Microbiota-Sparing, Live Biotherapeutic Anti-Infective for Clostridioides difficileR21AI169791 · NIAID · UNIVERSITY OF ARIZONA · PI VEDANTAM, GAYATRI · 2022 to 2023
$409k
BLRD VA I01 BX001183BLRD VA IK6 BX003789NIAID NIH HHS R21 AI169791
6 · The paper itself

Abstract

Background: Methods: Diarrheic stool specimens from patients with clinical suspicion of CDI were obtained over an eight-year period (2015-2022) from all inpatient and outpatient Units of a > 600-bed Medical Center in Southern Arizona. Clinical laboratory EIA testing identified Results: Of 8,910 diarrheic specimens that underwent diagnostic testing, 1733 (19.4%) harbored Conclusion: Our study highlights the dominance of Toxin EIA-negative CDI specimens in a clinical setting and the high frequency of known virulent ribotypes in these specimens. Therefore, a careful reevaluation of the clinical relevance of diagnostically-discrepant specimens particularly in the context of missed CDI diagnoses and

Indexed as

Clostridioides difficilediscrepantlongitudinalprevalenceribotypingsurveillance

Identifiers

PMID37928470
PMCPMC10622765
OpenAlexW4387742420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.