Evidence map›Paper›PMID 37928451›Full record

ArticleClinical Medicine Insights. Oncology2023

The Investigation of the Association Between the

Mehrnoush Azadeh Jouneghani, Fatemeh Keshavarzi, Nahid Haghnazari, Zahra Hooshmandi, Sabrieh Amini

Open access · goldAbstract read
In one paragraph

Article in Clinical Medicine Insights. Oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. The Association ofInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mehrnoush Azadeh JouneghaniDepartment of Biology, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran.
Fatemeh KeshavarziDepartment of Biology, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran.ORCID https://orcid.org/0000-0002-1131-107X
Nahid HaghnazariDepartment of Biology, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran.
Zahra HooshmandiDepartment of Biology, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran.
Sabrieh AminiDepartment of Biology, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran.
Islamic Azad University Sanandaj Branch · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: B-cell leukemia/lymphoma 2 ( Methods: A microarray analysis was performed on the Genomic Spatial Event (GSE)29431 and GSE161533 datasets for breast and gastric cancers. Blood samples were taken from 222 (111 patients and 111 controls) and 210 (84 patients and 126 controls) individuals for breast and gastric cancers, respectively. Genomic DNA was extracted from the blood samples and genotyping was performed using real-time polymerase chain reaction (RT-PCR), followed by examining the high-temperature melting curve. Statistical analysis was conducted to examine the potential correlation between the rs1564483 polymorphism and the risk of breast and gastric cancers concerning pathological characteristics. Results: The results of the microarray showed that the Conclusions: In silico studies and calculations of the ΔG binding of micro ribonucleic acid (miRNA) hsa-miR-296-3p to the mutant and wild alleles of the rs15644833 single nucleotide polymorphism (SNP) have revealed that Bcl-2 mRNA expression in gastric cancer decreases, thus confirming the tumor suppressor role of the

Indexed as

BCL-2 genebreast cancergastric cancermiR-296-3prs1564483

Identifiers

PMID37928451
PMCPMC10625176
OpenAlexW4388307788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.