Evidence map›Paper›PMID 37928405›Full record

ArticleGEN biotechnology2023

Generative Artificial Intelligence-Assisted Protein Design Must Consider Repurposing Potential.

Sean Ekins, Maximilian Brackmann, Cédric Invernizzi, Filippa Lentzos

Abstract read
In one paragraph

Article in GEN biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sean EkinsCollaborations Pharmaceuticals, Inc., Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0002-5691-5790
Maximilian BrackmannSpiez Laboratory, Federal Department of Defence, Civil Protection and Sports, Spiez, Switzerland.
Cédric InvernizziSpiez Laboratory, Federal Department of Defence, Civil Protection and Sports, Spiez, Switzerland.ORCID https://orcid.org/0000-0002-9807-5195
Filippa LentzosDepartment of War Studies and King's College London, London, United Kingdom.

Funding

Centralized assay datasets for modelling support of small drug discovery organizationsR44GM122196 · NIGMS · COLLABORATIONS PHARMACEUTICALS, INC. · PI EKINS, SEAN · 2018 to 2022
$3.3M
NIGMS NIH HHS R44 GM122196
6 · The paper itself

Abstract

Generative artificial intelligence software used for chemical and protein design has repurposing potential. We propose careful discussion in the biotech community on security considerations of such technologies and serious consideration of restrictions to control who can access the software and what applications it is used for.

Identifiers

PMID37928405
PMCPMC10623615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.