Evidence map›Paper›PMID 37928343›Full record

ArticleBioinformatics advances2023

ProbioMinServer: an integrated platform for assessing the safety and functional properties of potential probiotic strains.

Yen-Yi Liu, Chu-Yi Hsu, Ya-Chu Yang, Chien-Hsun Huang, Chih-Chieh Chen

Abstract read
In one paragraph

Article in Bioinformatics advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Draft genome sequence ofMicrobiology resource announcements · 2026
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  11. Probiotic Development Strategy Centered on Stability and Regulatory Considerations.Comprehensive reviews in food science and food safety · 2026
    Review
  12. Article
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  18. Whole-Genome Sequencing of ThreeJournal of microbiology and biotechnology · 2024
    Article
  19. Article
  20. International journal of systematic and evolutionary microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yen-Yi LiuDepartment of Biology, National Changhua University of Education, Changhua 500207, Taiwan.
Chu-Yi HsuInstitute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 804201, Taiwan.
Ya-Chu YangInstitute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 804201, Taiwan.
Chien-Hsun HuangBioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu 300193, Taiwan.
Chih-Chieh ChenInstitute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 804201, Taiwan.ORCID https://orcid.org/0000-0002-5844-8428

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motivation: ProbioMinServer is a platform designed to help researchers access information on probiotics regarding a wide variety of characteristics, such as safety (e.g. antimicrobial resistance, virulence, pathogenic, plasmid, and prophage genes) and functionality (e.g. functional classes, carbohydrate-active enzyme, and metabolite gene cluster profile). Because probiotics are functional foods, their safety and functionality are a crucial part of health care. Genomics has become a crucial methodology for investigating the safety and functionality of probiotics in food and feed. This shift is primarily attributed to the growing affordability of next-generation sequencing technologies. However, no integrated platform is available for simultaneously evaluating probiotic strain safety, investigating probiotic functionality, and identifying known phylogenetically related strains. Results: Thus, we constructed a new platform, ProbioMinServer, which incorporates these functions. ProbioMinServer accepts whole-genome sequence files in the FASTA format. If the query genome belongs to the 25 common probiotic species collected in our database, the server performs a database search and analyzes the core-genome multilocus sequence typing. Front-end applications were implemented in JavaScript with a bootstrap framework, and back-end programs were implemented using PHP, Perl, and Python. ProbioMinServer can help researchers quickly and easily retrieve information on the safety and functionality of various probiotics. Availability and implementation: The platform is available at https://probiomindb.imst.nsysu.edu.tw.

Identifiers

PMID37928343
PMCPMC10625473

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.