ReviewDigital health
Conversational artificial intelligence interventions to support smoking cessation: A systematic review and meta-analysis.
Review in Digital health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Natural Language Processing Chatbot-Based Interventions for Improvement of Diet, Physical Activity, and Tobacco Smoking Behaviors: Systematic Review.JMIR mHealth and uHealth · 2025Pooled it
- Development and efficacy testing of an artificial intelligence enabled treatment package (eDOSTHI) for tobacco cessation: study protocol for a randomized controlled trial.BMC psychiatry · 2026Trial
- Conversational Chatbot for Cigarette Smoking Cessation: Results From the 11-Step User-Centered Design Development Process and Randomized Controlled Trial.JMIR mHealth and uHealth · 2024Trial
- Short-Term Efficacy of the Artificial Intelligence HeartBot II in Increasing Awareness and Knowledge of Heart Attack in Women: Protocol for a Randomized Controlled Trial With a Waitlist Control.JMIR research protocols · 2026Article
- Evaluation of the Feasibility and Acceptability of Perfect Fit, a Virtual Coach-Based mHealth Intervention for Smoking Cessation and Physical Activity in Adults: Mixed Methods Study.JMIR human factors · 2026Article
- Safety Mechanisms and Risk Mitigation in Generative AI Mental Health Chatbots: A Systematic Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Instant messaging-delivered brief motivational interviewing for noncommunicable disease patients with no intention to quit smoking.NPJ digital medicine · 2026Article
- Enhancing Detection of Message Intents in a Mobile Health Smoking-Cessation Intervention Using Large Language Model Fine-Tuning, Data Downsampling, and Error Correction: Algorithm Development and Validation.Journal of medical Internet research · 2026Article
- Artificial intelligence and tobacco use: A bibliometric analysis 1997-2026.Tobacco induced diseases · 2026Article
- User experience and safety of generative AI-based mental health chatbots: Scoping review protocol.PloS one · 2026Article
- Recent Advances in AI-Driven Mobile Health Enhancing Healthcare-Narrative Insights into Latest Progress.Bioengineering (Basel, Switzerland) · 2025Review
- AI-Enabled Personalized Smoking Cessation Intervention With the Aipaca Chatbot: Mixed Methods Feasibility Study.JMIR formative research · 2025Observational
- Critical Appraisal Tools for Evaluating Artificial Intelligence in Clinical Studies: Scoping Review.Journal of medical Internet research · 2025Article
- Artificial Intelligence in Medicine.Thoracic research and practice · 2025Article
- Implementation of a Digital Health Intervention (CHAMP) for Self-Monitoring of Hypertension: Protocol for 3 Interlinked Implementation Studies.JMIR research protocols · 2025Article
- AI HeartBot to Increase Women's Awareness and Knowledge of Heart Attacks: Nonrandomized, Quasi-Experimental Study.JMIR cardio · 2025Article
- Concordance of an Artificial Intelligence Model (ChatGPT 4.0) with Physician Decisions in Smoking Cessation Clinics: A Comparative Evaluation.Healthcare (Basel, Switzerland) · 2025Article
- Effectiveness of family-based behavioral intervention for smoking cessation in low-income households: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- Effectiveness and Adherence of Standalone Digital Tobacco Cessation Modalities: A Systematic Review of Systematic Reviews.Healthcare (Basel, Switzerland) · 2025Review
- An Examination of Generative AI Response to Suicide Inquires: Content Analysis.JMIR mental health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Conversational artificial intelligence (chatbots and dialogue systems) is an emerging tool for tobacco cessation that has the potential to emulate personalised human support and increase engagement. We aimed to determine the effect of conversational artificial intelligence interventions with or without standard tobacco cessation interventions on tobacco cessation outcomes among adults who smoke, compared to no intervention, placebo intervention or an active comparator. Methods: A comprehensive search of six databases was completed in June 2022. Eligible studies included randomised controlled trials published since 2005. The primary outcome was sustained tobacco abstinence, self-reported and/or biochemically validated, for at least 6 months. Secondary outcomes included point-prevalence abstinence and sustained abstinence of less than 6 months. Two authors independently extracted data on cessation outcomes and completed the risk of bias assessment. Random effects meta-analysis was conducted. Results: From 819 studies, five randomised controlled trials met inclusion criteria (combined sample size Conclusion: We found limited but promising evidence on the effectiveness of conversational artificial intelligence interventions for tobacco cessation. Although all studies found benefits from conversational artificial intelligence interventions, results should be interpreted with caution due to high heterogeneity. Given the rapid evolution and potential of artificial intelligence interventions, further well-designed randomised controlled trials following standardised reporting guidelines are warranted in this emerging area.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.