Evidence map›Paper›PMID 37928321›Full record

ArticleMolVa : Workshop on Molecular Graphics and Visual Analysis of Molecular Data 20202020

Mesoscope: A Web-based Tool for Mesoscale Data Integration and Curation.

L Autin, M Maritan, B A Barbaro, A Gardner, A J Olson, M Sanner, D S Goodsell

Abstract read
In one paragraph

Article in MolVa : Workshop on Molecular Graphics and Visual Analysis of Molecular Data 2020, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Integrative modeling of JCVI-Syn3A nucleoids with a modular approach.Current research in structural biology · 2024
    Article
  3. Integrative illustration of a JCVI-syn3A minimal cell.Journal of integrative bioinformatics · 2022
    Article
  4. Building Structural Models of a Whole Mycoplasma Cell.Journal of molecular biology · 2022
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

L AutinDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0002-2197-191X
M MaritanDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0001-9901-1153
B A BarbaroDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0003-2156-7877
A GardnerDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0003-3317-2856
A J OlsonDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0003-0558-4618
M SannerDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0001-9342-327X
D S GoodsellDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0002-5932-2130

Funding

Modeling and Interacting with the Visible Molecular CellR01GM120604 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI AUTIN, LUDOVIC · 2016 to 2025
$4.2M
NIGMS NIH HHS R01 GM120604
6 · The paper itself

Abstract

Interest is growing for 3D models of the biological mesoscale, the intermediate scale between the nanometer scale of molecular structure and micrometer scale of cellular biology. However, it is currently difficult to gather, curate and integrate all the data required to define such models. To address this challenge we developed Mesoscope (mesoscope.scripps.edu/beta), a web-based data integration and curation tool. Mesoscope allows users to begin with a listing of molecules (such as data from proteomics), and to use resources at UniProt and the PDB to identify, prepare and validate appropriate structures and representations for each molecule, ultimately producing a portable output file used by CellPACK and other modeling tools for generation of 3D models of the biological mesoscale. The availability of this tool has proven essential in several exploratory applications, given the high complexity of mesoscale models and the heterogeneity of the available data sources.

Indexed as

Applied computing → BioinformaticsComputing methodologies → Graphics systems and interfaces

Identifiers

PMID37928321
PMCPMC10624244

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.