Evidence map›Paper›PMID 37928045›Full record

ArticleHeliyon2023

Validation and development of RP-HPLC method for quantification of glibenclamide in rat plasma and its application to pharmacokinetic studies in wistar rats.

Khalid Bashir Mir, Vidushi Abrol, Taha U Wani, Ishrat Jan, Nasseb Singh, Nisar A Khan, Alamgir A Dar, Rania Mohammad Sabri Sultan, Showkat A Lone, Mohamed A M Iesa and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 2 countries.

Khalid Bashir MirDepartment of Pharmaceutical Sciences, University of Kashmir, J&K, 190001, India.
Vidushi AbrolFermentation & Microbial Biotechnology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi, J&K, 180001, India.
Taha U WaniDepartment of Pharmaceutical Sciences, University of Kashmir, J&K, 190001, India.
Ishrat JanResearch Centre for Residue and Quality Analysis, Sher-e-Kashmir University of Agricultural Sciences & Technologyof Kashmir, Shalimar Campus, Srinagar, J&K, 190025, India.
Nasseb SinghSynthetic Organic Chemistry Laboratory, Faculty of Sciences, Shri Mata Vaishno Devi University, Katra, 182320, India.
Nisar A KhanDepartment of Pharmaceutical Sciences, University of Kashmir, J&K, 190001, India.
Alamgir A DarResearch Centre for Residue and Quality Analysis, Sher-e-Kashmir University of Agricultural Sciences & Technologyof Kashmir, Shalimar Campus, Srinagar, J&K, 190025, India.
Rania Mohammad Sabri SultanKing Abdul-Aziz University Faculty of Science, Department of Biological Sciences, Saudi Arabia.
Showkat A LoneDepartment of Basic Sciences, College of Science and Theoretical Studies, Saudi Electronic University, Jeddah-M, Riyadh, 11673, Saudi Arabia.
Mohamed A M IesaDepartment of Physiology, Al Qunfudah Medical College, Umm Al Qura University, Mecca, Saudi Arabia.
Sadeq K AlhagBiology Department, College of Science and Arts, King Khalid University, Muhayl Asser, 61913, Saudi Arabia.
Laila A Al-ShuraymBiology Department, Faculty of Science, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Nawal HelmBiochemistry Departments, College of Science, Unversity of Jeddah, Jeddah, 23218, Saudi Arabia.
Ammar Al-FargaDepartment of Biochemistry, College of Science, University of Jeddah, Jeddah, 23218, Saudi Arabia.
University of Kashmir · INSher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir · INUniversity of Jeddah · SAIndian Institute of Integrative Medicine · INKing Abdul Aziz University Hospital · SAKing Khalid University · SAPrincess Nourah bint Abdulrahman University · SASaudi Electronic University · SAShri Mata Vaishno Devi University · INUmm al-Qura University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we report a novel, simple, specific, accurate and cost-friendly validated reverse phase-high performance liquid chromatographic (RP-HPLC) method for the quantification of second generation sulphonylurea based antidiabetic drug, glibenclamide (GLB) in rat plasma and its application to calculate pharmacokinetic parameters in wistar rats. The internal standard used was flufenamic acid. The chromatographic separation was conducted on C

Indexed as

GlibenclamideMethod validationPharmacokineticsPlasmaRP-HPLCWistar rats

Identifiers

PMID37928045
PMCPMC10623144
OpenAlexW4387708820

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.