Evidence map›Paper›PMID 37927956›Full record

ArticleJournal of inflammation research2023

Effect of Hyperbaric Oxygen Intervention on Oxidative Stress and Expression of Nerve Growth Factor in Patients with Craniocerebral Injury.

Bingyan Ren, Hanbin Ye, Wenyuan Shan, Xuelei Tao, Zi Ye

Abstract read
In one paragraph

Article in Journal of inflammation research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bingyan Ren *Department of Emergency, the Second Affiliated Hospital of Nantong University, Nantong First People's Hospital, Nantong, People's Republic of China.
Hanbin Ye *Department of Neurosurgery, the Second Affiliated Hospital of Nantong University, Nantong First People's Hospital, Nantong, People's Republic of China.
Wenyuan ShanDepartment of Neurosurgery, the Fourth Affiliated Hospital of Nantong University, Nantong Fourth People's Hospital, Nantong, People's Republic of China.
Xuelei TaoDepartment of Neurosurgery, Nantong Second People's Hospital, Nantong, People's Republic of China.
Zi YeDepartment of Neurosurgery, the Second Affiliated Hospital of Nantong University, Nantong First People's Hospital, Nantong, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To examine the impact of hyperbaric oxygen intervention on oxidative stress and nerve growth factor in patients with craniocerebral injury. Methods: Using the random number table method, 40 patients with craniocerebral injury who were treated at the First People's Hospital of Nantong were randomly assigned to either the control group or the hyperbaric oxygen group, with 20 patients in each group. The control group received routine intervention for clinical traumatic brain injury, while the hyperbaric oxygen group received additional hyperbaric oxygen intervention during the 7 to 30 days of routine intervention. Indicators of oxidative stress and nerve growth factor levels were compared between the two groups at the time of admission and 30 days after therapy. Results: The serum levels of superoxide dismutase, endothelium-derived relaxing factor-nitric oxide, and nerve growth factor in the hyperbaric oxygen group increased more significantly than in the control group. The serum malondialdehyde concentration was also significantly reduced in the hyperbaric oxygen group. Conclusion: Hyperbaric oxygen intervention can successfully lower systemic oxidative stress response and increase the expression level of nerve growth factor in patients with craniocerebral injury.

Indexed as

craniocerebral injuryhyperbaric oxygennerve growth factoroxidative stress

Identifiers

PMID37927956
PMCPMC10624337

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.