Evidence map›Paper›PMID 37927807›Full record

ReviewCancer diagnosis & prognosis

Heat Shock Proteins' Expression Profiles in Odontogenic Ameloblastomas and Cysts.

Vasiliki Mathiou, Evangelos Tsiambas, Sotirios Maipas, Irene Thymara, Sofaniki Mastronikoli, Dimitrios Peschos, Konstantinos I Tsamis, Andreas C Lazaris, Nikolaos Kavantzas, Panagiotis Stathopoulos

Abstract readReview
In one paragraph

Review in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Chaperonin in health and disease.Molecular biomedicine · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vasiliki MathiouMathiou Dental Clinic, Athens, Greece.
Evangelos TsiambasDepartment of Cytology, 417 Veterans Army Hospital (NIMTS), Athens, Greece.
Sotirios Maipas1st Department of Pathology, Medical School, National and Kapodistrian University, Athens, Greece.
Irene Thymara1st Department of Pathology, Medical School, National and Kapodistrian University, Athens, Greece.
Sofaniki MastronikoliBrighton and Sussex Medical School, Brighton, U.K.
Dimitrios PeschosDepartment of Physiology, Medical School, University of Ioannina, Ioannina, Greece.
Konstantinos I TsamisDepartment of Physiology, Medical School, University of Ioannina, Ioannina, Greece.
Andreas C Lazaris1st Department of Pathology, Medical School, National and Kapodistrian University, Athens, Greece.
Nikolaos Kavantzas1st Department of Pathology, Medical School, National and Kapodistrian University, Athens, Greece.
Panagiotis StathopoulosDepartment of Maxillofacial Surgery, ''KAT'' General Hospital, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumors and cysts with odontogenic origin represent a family of lesions with specific histo-genetic and clinical characteristics. Among them, ameloblastomas are common benign neoplasms, predominantly detected in the anatomic areas of the jaws and also in the mandible and maxilla. Although they are characterized by a slow and stable growing pattern, a subset of them shows a tendency for local tissue invasiveness and partially increased recurrence rates after surgical excision. Furthermore, heat shock proteins (HSPs) are potentially implicated in ameloblastoma onset and progression. HSPs regulate the folding and refolding of proteins and are induced in response to oxidative stress. They are crucial members of the chaperone intracellular system and are categorized based on their molecular weight (i.e., HSP27, HSP60, HSP70, HSP90). In the current review, we describe HSPs origin and function, focusing on their deregulation mechanisms and impact predominantly on ameloblastomas and also on inflammatory and developmental odontogenic cystic lesions.

Indexed as

ameloblastomacystheat shock proteinsIntracellularodontogenicreviewstress

Identifiers

PMID37927807
PMCPMC10619569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.