Evidence map›Paper›PMID 37927786›Full record

ArticlePeerJ2023

The recombinant BMP-2 loaded silk fibroin microspheres improved the bone phenotype of mild osteogenesis imperfecta mice.

Ting Fu, Yi Liu, Zihan Wang, Yaqing Jing, Yuxia Zhao, Chenyi Shao, Zhe Lv, Guang Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ting Fu *Department of Genetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Yi Liu *Department of Genetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Zihan WangDepartment of Genetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Yaqing JingDepartment of Genetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Yuxia ZhaoDepartment of Genetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Chenyi ShaoDepartment of Genetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Zhe LvDepartment of Genetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Guang LiDepartment of Genetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Tianjin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteogenesis imperfecta (OI) is an inherited congenital disorder, characterized primarily by decreased bone mass and increased bone fragility. Bone morphogenetic protein-2 (BMP-2) is a potent cytokine capable of stimulating bone formation, however, its rapid degradation and unanticipated

Indexed as

FibroinsOsteogenesis ImperfectaAnimalsMiceMicrospheresOsteogenesisPhenotypeFibroinsBone morphogenetic protein-2Congenital diseaseMicro CTOsteogenesis imperfectaSilk fibroin microspheresSustain release

Identifiers

PMID37927786
PMCPMC10621593
OpenAlexW4388097599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.