ArticleCureus2023
Ulcerative Colitis Flare Post Isotretinoin Use: A Case Report.
Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 0 citations in OpenAlex.
- Drug-associated inflammatory bowel disease: a real-world pharmacovigilance study using the FAERS and JADER databases.Frontiers in immunology · 2026Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ulcerative colitis (UC) is an inflammatory bowel disease characterized by chronic intestinal inflammation. We present a case of UC flare induced by isotretinoin, a medication commonly used for the treatment of severe acne. A 36-year-old male with a history of UC in remission presented with moderate-severe cystic acne and was started on isotretinoin. After four months of treatment, he developed symptoms of UC flare, including bloody diarrhea. A colonoscopy revealed ulcerative pancolitis, and isotretinoin was discontinued. The patient was subsequently treated with adalimumab and azathioprine, achieving good disease control. This case highlights the potential link between isotretinoin and UC exacerbation, suggesting the need for further research to understand the underlying mechanisms and assess the risk associated with isotretinoin use in patients with UC.
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Registered trials
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