ReviewFrontiers in pharmacology2023
Chemical composition, biological activities, and quality standards of hawthorn leaves used in traditional Chinese medicine: a comprehensive review.
Review in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Discovery of Pancreatic Lipase Inhibitory and Antimicrobial Constituents in Crataegi Folium by High-Performance Thin-Layer Chromatography-Bioautography-Mass Spectrometry.Journal of separation science · 2026Article
- Integrating UHPLC-Q-TOF-MS, Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulations to Reveal the Potential Mechanisms of Yiguanjian Decoction in Treating Liver Cancer.Chemistry & biodiversity · 2026Article
- Antibacterial efficacy and mechanisms of hawthorn leaf extract against poultry-derived Staphylococcus aureus and Escherichia coli: potential as natural food preservatives.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Flavonoids in Medicine and Food Homology Substances: Structure-Activity Relationship, Application Challenges, and Cutting-Edge Technological Breakthroughs.Foods (Basel, Switzerland) · 2026Review
- The Hawthorn (Foods (Basel, Switzerland) · 2026Review
- Optimization of Conventional and Ultrasound-Assisted Extraction to Maximize Recovery of Total Phenolic Content and In Vitro Antioxidant Activity fromAntioxidants (Basel, Switzerland) · 2025Article
- Targeted quantitative analysis of the effect of hawthorn leaves on volatiles and nonvolatile polyphenols and amino acids in hawthorn wine.Food chemistry: X · 2025Article
- The Effect of Hawthorn Red Pigment on Meridian Voltage: An Experimental Study on Traditional Efficacy and Modern Application Value.Bioelectricity · 2025Article
- Optimization of Microwave-Assisted Extraction of Polyphenols fromAntioxidants (Basel, Switzerland) · 2025Article
- Analysis of Adverse Reactions Associated with the Use ofPharmaceuticals (Basel, Switzerland) · 2024Article
- Hawthorn with "homology of medicine and food": a review of anticancer effects and mechanisms.Frontiers in pharmacology · 2024Review
- Integrating Network Pharmacology and Experimental Validation to Identifying Key Herbal Components and Targets for Liver Cancer.Iranian journal of pharmaceutical research : IJPRArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hawthorn leaves also known as crataegi foilum, are a combination of botanical drugs used commonly in Traditional Chinese Medicine. Hawthorn, the plant from which hawthorn leaves are prepared, is distributed in Northeast China, North China, and other regions in China. Hawthorn leaves are known to activate blood circulation and eliminate stasis, invigorating Qi, eliminating turbidity, and reducing the levels of lipids. So far, over a hundred compounds have been isolated from hawthorn leaves, including flavonoids, terpenoids, lignans, organic acids, and nitrogenous compounds. Hawthorn leaves are used for the treatment of hypertension, protecting against ischemic injury, angina, hyperglycemia, hyperlipidemia, and certain other conditions. Several of the currently available clinical preparations also use hawthorn leaves as raw materials, such as Yixintong capsules, Xinan capsules, etc. The present report systematically reviews the chemical composition, biological activities, and quality standards of hawthorn leaves, to provide a scientific basis and reference for detailed research on hawthorn leaves.
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