Evidence map›Paper›PMID 37927501›Full record

SynthesisFrontiers in nutrition2023

The effect of flaxseed supplementation on sex hormone profile in adults: a systematic review and meta-analysis.

Vali Musazadeh, Ahmad Nazari, Mohammad Natami, Zahra Hajhashemy, Kimia Sadat Kazemi, Fereshte Torabi, Amir Hossein Moridpour, Mahdi Vajdi, Gholamreza Askari

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Vali MusazadehStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Ahmad NazariTehran University of Medical Sciences, Tehran, Iran.
Mohammad NatamiDepartment of Urology, Shahid Mohammadi Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Zahra HajhashemyStudent Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Kimia Sadat KazemiFaculty of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Fereshte TorabiFaculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Amir Hossein MoridpourStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Mahdi VajdiStudent Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Gholamreza AskariDepartment of Community Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Isfahan University of Medical Sciences · IRTabriz University of Medical Sciences · IRHormozgan University of Medical Sciences · IRMashhad University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inconsistent data suggest that flaxseed supplementation may have a role in sex hormones. We aimed to carry out a systematic review and meta-analysis of randomized controlled trials (RCTs) investigating effects of flaxseed supplementation on sex hormone profile. PubMed, Scopus, Embase, Cochrane Library, Web of Science databases, and Google Scholar were searched up to March 2023. Standardized mean difference (SMD) was pooled using a random-effects model. Sensitivity analysis, heterogeneity, and publication bias were reported using standard methods. The quality of each study was evaluated with the revised Cochrane risk-of-bias tool for randomized trials, known as RoB 2. Finding from ten RCTs revealed that flaxseed supplementation had no significant alteration in follicle-stimulating hormone (FSH) (SMD: -0.11; 95% CI: -0.87, 0.66:

Indexed as

flaxseedgendermeta-analysissex hormonessystematic review

Identifiers

PMID37927501
PMCPMC10623424
OpenAlexW4387810205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.