Evidence map›Paper›PMID 37926784›Full record

ArticleGeroScience2024

Socioeconomic status, lifestyle and risk of incident dementia: a prospective cohort study of 276730 participants.

Ya-Nan Ou, Yan-Bo Zhang, Yu-Zhu Li, Shu-Yi Huang, Wei Zhang, Yue-Ting Deng, Bang-Sheng Wu, Lan Tan, Qiang Dong, An Pan and 5 more

Abstract read
In one paragraph

Article in GeroScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Superficial white matter and gray matter jointly support cognition among older adults in India.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
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  5. Review
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  13. Article
  14. Social determinants of dementia: A scoping review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ya-Nan OuDepartment of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, 266071, China.
Yan-Bo ZhangDepartment of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.
Yu-Zhu LiInstitute of Science and Technology for Brain-inspired Intelligence, Fudan University, Shanghai, 200433, China.
Shu-Yi HuangDepartment of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai, 200040, China.
Wei ZhangInstitute of Science and Technology for Brain-inspired Intelligence, Fudan University, Shanghai, 200433, China.
Yue-Ting DengDepartment of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai, 200040, China.
Bang-Sheng WuDepartment of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai, 200040, China.
Lan TanDepartment of Neurology, Qingdao Municipal Hospital, Qingdao University, Qingdao, 266071, China. dr.tanlan@163.com.
Qiang DongDepartment of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai, 200040, China.
An PanDepartment of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.
Ren-Jie ChenSchool of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, 200040, China.
Jian-Feng FengInstitute of Science and Technology for Brain-inspired Intelligence, Fudan University, Shanghai, 200433, China.
A David SmithDepartment of Pharmacology, University of Oxford, Oxford, OX1 3QT, UK.
Wei ChengDepartment of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai, 200040, China.
Jin-Tai YuDepartment of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai Medical College, Fudan University, Shanghai, 200040, China. jintai_yu@fudan.edu.cn.ORCID 0000-0002-7686-0547

Funding

111 Project B18015Excellence 2025 Talent Cultivation Program at Fudan University 3030277001National Natural Science Foundation of China 82071201National Natural Science Foundation of China 82071997Research Start-up Fund of Huashan Hospital 2022QD002Science and Technology Innovation 2030 Major Projects 2022ZD0211600Shanghai Municipal Science and Technology Major Project 2018SHZDZX01Shanghai Rising-Star Program 21QA1408700Shanghai Talent Development Funding for The Project 2019074
6 · The paper itself

Abstract

Healthy lifestyle might alleviate the socioeconomic inequities in health, but the extent of the joint and interactive effects of these two factors on dementia are unclear. This study aimed to detect the joint and interactive associations of socioeconomic status (SES) and lifestyle factors with incident dementia risk, and the underlying brain imaging alterations. Cox proportional hazards analysis was performed to test the joint and interactive associations. Partial correlation analysis was performed to reflect the brain imaging alterations. A total of 276,730 participants with a mean age of 55.9 (±8.0) years old from UK biobank were included. Over 8.5 (±2.6) years of follow-up, 3013 participants were diagnosed with dementia. Participants with high SES and most healthy lifestyle had a significantly lower risk of incident dementia (HR=0.19, 95% CI=0.14 to 0.26, P<2×10

Indexed as

Alzheimer DiseaseBrainHumansLife StyleProspective StudiesSocial ClassDementiaHealthy lifestyleSocioeconomic statusUK Biobank

Identifiers

PMID37926784
PMCPMC10828350

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.