Evidence map›Paper›PMID 37926770›Full record

ArticleStress and health : journal of the International Society for the Investigation of Stress2024

Trajectories of depressive symptoms early in the course of bereavement: Patterns, psychosocial factors and risk of prolonged grief.

Marzieh Majd, Michelle A Chen, Diana A Chirinos, Ryan L Brown, Angie S LeRoy, Kyle W Murdock, E Lydia Wu-Chung, Julian F Thayer, Christopher P Fagundes

Abstract read
In one paragraph

Article in Stress and health : journal of the International Society for the Investigation of Stress, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marzieh MajdDepartment of Psychological Sciences, Rice University, Houston, Texas, USA.ORCID https://orcid.org/0000-0002-7367-663X
Michelle A ChenInstitute of Policy Research, Northwestern University, Evanston, Illinois, USA.
Diana A ChirinosDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Ryan L BrownDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, USA.ORCID https://orcid.org/0000-0003-2844-5928
Angie S LeRoyDepartment of Psychology & Neuroscience, Baylor University, Waco, Texas, USA.
Kyle W MurdockDepartment of Biobehavioral Health, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0001-7982-443X
E Lydia Wu-ChungDepartment of Psychological Sciences, Rice University, Houston, Texas, USA.
Julian F ThayerDepartment of Psychological Sciences, University of California-Irvine, Irvine, California, USA.
Christopher P FagundesDepartment of Psychological Sciences, Rice University, Houston, Texas, USA.

Funding

Individual differences in dementia spousal caregiver burden: A biobehavioral approach revisionR01AG062690 · NIA · RICE UNIVERSITY · PI FAGUNDES, CHRISTOPHER PAUL · 2019 to 2023
$4.3M
Project Heart: Biobehavioral Effects on Cardiovascular Risk for Bereaved SpousesR01HL127260 · NHLBI · RICE UNIVERSITY · PI FAGUNDES, CHRISTOPHER PAUL · 2015 to 2019
$4.1M
Developing an intervention targeting sleep disturbances among minority bereaved individualsK01HL149987 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CHIRINOS, DIANA ANDREA · 2020 to 2024
$809k
Behavioral, Neural, and Molecular Correlates of Response Inhibition in Bipolar DisorderK01MH137689 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Marzieh Majd · 2025 to 2026
$366k
A Grieving Heart: Does Feeling Burdensome to Others Impact Inflammatory Outcomes During Spousal Bereavement?F32HL146064 · NHLBI · RICE UNIVERSITY · PI LEROY, ANGIE S · 2019 to 2022
$220k
Neighborhood-level Structural Racism and Cardiovascular Health Among African American Youth and Young AdultsF32HL164050 · NHLBI · NORTHWESTERN UNIVERSITY · PI CHEN, MICHELLE A. · 2022 to 2024
$218k
From stress to dementia risk: An examination of psychological, immunological, and neurobiological mechanisms underlying increased risk for Alzheimer’s disease and related dementias in widow(er)sF31AG074648 · NIA · RICE UNIVERSITY · PI WU-CHUNG, E. LYDIA · 2022 to 2024
$116k
Adverse Childhood Experiences and Individual Differences among Dementia Spousal Caregivers: A Biobehavioral Approach to Stress Across the LifespanF31AG069439 · NIA · RICE UNIVERSITY · PI CHEN, MICHELLE A. · 2020 to 2021
$90k
NHLBI NIH HHS 1K01HL149987-01A1NHLBI NIH HHS 1R01HL127260-01NHLBI NIH HHS 5F32HL164050-02NHLBI NIH HHS F32 HL146064NHLBI NIH HHS F32HL146064-03NHLBI NIH HHS F32 HL164050NHLBI NIH HHS K01 HL149987NHLBI NIH HHS R01 HL127260NIA NIH HHS 1F31AG074648NIA NIH HHS 3R01AG062690-02S1NIA NIH HHS 5F31AG069439-02NIA NIH HHS F31 AG069439NIA NIH HHS F31 AG074648NIA NIH HHS R01 AG062690NIMH NIH HHS K01 MH137689
6 · The paper itself

Abstract

In the context of bereavement, little is known about the mechanisms that differentiate normative adjustment patterns from those that may indicate potential psychopathology. This study aimed to replicate and extend previous work by (1) characterizing the trajectories of depressive symptoms from 3 to 12 months after the loss of a spouse, (2) examining whether (a) childhood maltreatment and attachment style predicted distinct depression trajectories, and (b) different depression trajectories were associated with the risk of prolonged grief at 12 months post-loss. Recently bereaved individuals (N = 175) completed self-report assessments at 3, 4, 6, and 12-months post-loss. Trajectories of depressive symptoms were estimated using group-based trajectory modelling. Four distinct trajectories of depressive symptoms were identified: (1) resilience (minimal/no depression across time points; 45%), (2) moderate depression-improved (alleviated to 'mild' by 12 months; 31%), (3) severe depression-improved (alleviated to 'moderate' by 12 months; 15%), and (4) chronic depression ('severe' symptoms across time points; 9%). Higher childhood maltreatment predicted a greater likelihood of belonging to the 'severe depression-improved' and 'chronic depression' groups than the 'resilient' and 'moderate depression-improved' groups. Widow(er)s with higher attachment anxiety were more likely to belong to the 'severe depression-improved' and 'chronic depression' groups than the 'resilient' group. The trajectory groups with persistent levels of depressive symptoms up until 6 months were more likely to exhibit prolonged grief at 12 months post-loss. Changes from pre-loss functioning cannot be estimated. Our findings provide insight into the early identification of post-loss prolonged grief.

Indexed as

BereavementDepressionGriefAdultAgedFemaleHumansMaleMiddle AgedObject AttachmentResilience, PsychologicalRisk Factorschildhood maltreatmentdepressionlongitudinal trajectoriesspousal loss

Identifiers

PMID37926770
PMCPMC11069593

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.