Evidence map›Paper›PMID 37926551›Full record

ArticleInternal medicine (Tokyo, Japan)2024

Zinc Administration Favorably Affects Prophylactic Therapy-refractory Migraine Attacks: A Case Series.

Ryosuke Fukazawa, Ryotaro Ishii, Yuki Higashimoto, Misaki Hanya, Yuki Shimizu, Makiko Shinomoto, Akihiro Fujii, Toshiki Mizuno

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ryosuke FukazawaDepartment of Neurology, Kyoto Prefectural University of Medicine, Japan.
Ryotaro IshiiDepartment of Neurology, Kyoto Prefectural University of Medicine, Japan.
Yuki HigashimotoDepartment of Neurology, Kyoto Prefectural University of Medicine, Japan.
Misaki HanyaDepartment of Neurology, Kyoto Prefectural University of Medicine, Japan.
Yuki ShimizuDepartment of Neurology, Kyoto Prefectural University of Medicine, Japan.
Makiko ShinomotoDepartment of Neurology, Kyoto Prefectural University of Medicine, Japan.
Akihiro FujiiDepartment of Neurology, Saiseikai Shiga Hospital, Japan.
Toshiki MizunoDepartment of Neurology, Kyoto Prefectural University of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Notably, certain nutrients are effective in preventing migraine. Nonetheless, zinc replacement therapy for migraine treatment has yet to be explored. We herein report four patients with migraine who were refractory to prophylactic therapy and whose headache frequency and severity improved with zinc supplementation. Zinc administration may be an option for treating patients with prophylaxis-refractory migraine. Further investigation is required to determine the efficacy of zinc replacement therapy as a treatment option for migraine.

Indexed as

Migraine DisordersZincHumansTreatment OutcomeZincmigrainenutritiontrophic factorszinc administrationzinc deficiency

Identifiers

PMID37926551
PMCPMC11189699

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.