Evidence map›Paper›PMID 37926535›Full record

ArticleInternal medicine (Tokyo, Japan)2024

Anti-NXP2 Antibody-positive Juvenile Dermatomyositis with Characteristic Fascial Thickening on Muscle Ultrasound and Improvement with Immunotherapy.

Koji Fukushima, Takeshi Yoshida, Hiroki Yamazaki, Naoko Takamatsu, Takashi Nagai, Yusuke Osaki, Masafumi Harada, Ichizo Nishino, Naoko Okiyama, Kazuma Sugie and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Koji FukushimaDepartment of Neurology, Tokushima University Hospital, Japan.
Takeshi YoshidaDepartment of Rheumatology, Chikamori Hospital, Japan.
Hiroki YamazakiDepartment of Neurology, Tokushima University Hospital, Japan.
Naoko TakamatsuDepartment of Neurology, Tokushima University Hospital, Japan.
Takashi NagaiDepartment of Pediatrics, Tokushima University Hospital, Japan.
Yusuke OsakiDepartment of Neurology, Tokushima University Hospital, Japan.
Masafumi HaradaDepartment of Radiology, Tokushima University Hospital, Japan.
Ichizo NishinoDepartment of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Japan.
Naoko OkiyamaDepartment of Dermatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan.
Kazuma SugieDepartment of Neurology, Nara Medical University School of Medicine, Japan.
Yuishin IzumiDepartment of Neurology, Tokushima University Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a 12-year-old boy who presented with a fever, erythematous rash on the cheeks, back pain, and dysphagia. Blood tests revealed increased creatine kinase levels, and muscle ultrasonography (MUS) revealed characteristic fascial thickening in the lumbar paraspinal muscles, where myalgia was prominent. Sarcoplasmic expression of myxovirus-resistant protein A on a muscle biopsy and the presence of anti-nuclear matrix protein 2 (NXP2) antibodies confirmed the diagnosis of dermatomyositis. Prednisolone and intravenous immunoglobulin therapy improved the clinical and laboratory parameters as well as fascial thickening. MUS is useful for evaluating fasciitis associated with anti-NXP2 autoantibodies and monitoring therapeutic efficacy.

Indexed as

AutoantibodiesDermatomyositisUltrasonographyAdenosine TriphosphatasesChildDNA-Binding ProteinsHumansImmunoglobulins, IntravenousImmunotherapyMalePrednisoloneRNA-Binding ProteinsTreatment OutcomeAdenosine TriphosphatasesAutoantibodiesDNA-Binding ProteinsImmunoglobulins, IntravenousMORC3 protein, humanPrednisoloneRNA-Binding Proteinsdermatomyositis sine dermatitisfasciitisjuvenile dermatomyositismuscle ultrasoundmyxovirus resistant protein Anuclear matrix protein 2

Identifiers

PMID37926535
PMCPMC11239255

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.