Evidence map›Paper›PMID 37926525›Full record

ArticleNMR in biomedicine2024

High-resolution spiral real-time cardiac cine imaging with deep learning-based rapid image reconstruction and quantification.

Junyu Wang, Marina Awad, Ruixi Zhou, Zhixing Wang, Xitong Wang, Xue Feng, Yang Yang, Craig Meyer, Christopher M Kramer, Michael Salerno

Open access · greenAbstract read
In one paragraph

Article in NMR in biomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Junyu WangDepartment of Medicine, Cardiovascular Medicine, Stanford University, Stanford, California, USA.
Marina AwadDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Ruixi ZhouSchool of Artificial Intelligence, Beijing University of Posts and Telecommunications, Beijing, China.
Zhixing WangDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0002-8189-0601
Xitong WangDepartment of Bioengineering, Stanford University, Stanford, California, USA.
Xue FengDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Yang YangDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
Craig MeyerDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Christopher M KramerDepartment of Medicine, Division of Cardiovascular, University of Virginia Health System, Charlottesville, Virginia, USA.
Michael SalernoDepartment of Medicine, Cardiovascular Medicine, Stanford University, Stanford, California, USA.
University of Virginia · USStanford Medicine · USBeijing University of Posts and Telecommunications · CNCity Of Hope National Medical Center · USStanford University · USUniversity of California, San Francisco · USUniversity of Virginia Health System · US

Funding

High-Resolution Whole Heart Quantitative CMR Perfusion Imaging in Ischemic Heart DiseaseR01HL131919 · NHLBI · UNIVERSITY OF VIRGINIA · PI ENNIS, DANIEL B · 2017 to 2021
$3.5M
Rapid Free-Breathing Self-Gated Spiral Pulse Sequences for Simultaneous Cine and T1 mappingR01HL155962 · NHLBI · UNIVERSITY OF VIRGINIA · PI SALERNO, MICHAEL · 2021 to 2024
$2.1M
NHLBI NIH HHS R01 HL131919NHLBI NIH HHS R01 HL155962NIH HHS HL155962NIH HHS R01 HL131919
6 · The paper itself

Abstract

The objective of the current study was to develop and evaluate a DEep learning-based rapid Spiral Image REconstruction (DESIRE) and deep learning (DL)-based segmentation approach to quantify the left ventricular ejection fraction (LVEF) for high-resolution spiral real-time cine imaging, including 2D balanced steady-state free precession imaging at 1.5 T and gradient echo (GRE) imaging at 1.5 and 3 T. A 3D U-Net-based image reconstruction network and 2D U-Net-based image segmentation network were proposed and evaluated. Low-rank plus sparse (L+S) served as the reference for the image reconstruction network and manual contouring of the left ventricle was the reference of the segmentation network. To assess the image reconstruction quality, structural similarity index, peak signal-to-noise ratio, normalized root-mean-square error, and blind grading by two experienced cardiologists (5: excellent; 1: poor) were performed. To assess the segmentation performance, quantification of the LVEF on GRE imaging at 3 T was compared with the quantification from manual contouring. Excellent performance was demonstrated by the proposed technique. In terms of image quality, there was no difference between L+S and the proposed DESIRE technique. For quantification analysis, the proposed DL method was not different to the manual segmentation method (p > 0.05) in terms of quantification of LVEF. The reconstruction time for DESIRE was ~32 s (including nonuniform fast Fourier transform [NUFFT]) per dynamic series (40 frames), while the reconstruction time of L+S with GPU acceleration was approximately 3 min. The DL segmentation takes less than 5 s. In conclusion, the proposed DL-based image reconstruction and quantification techniques enabled 1-min image reconstruction for the whole heart and quantification with automatic reconstruction and quantification of the left ventricle function for high-resolution spiral real-time cine imaging with excellent performance.

Indexed as

Deep LearningImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMagnetic Resonance Imaging, CineStroke VolumeVentricular Function, Leftcardiacdeep learningreal-time imagingspiral

Identifiers

PMID37926525
PMCPMC12258077
OpenAlexW4388399458

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.