Evidence map›Paper›PMID 37926453›Full record

ArticleSaudi medical journal2023

Clinical significance of elevated soluble T-cell immunoglobulin and mucin domain 1 and soluble P-selectin in individuals with obstructive sleep apnea-hypopnea syndrome.

Haidi Fan, Yanqiu Liu, Xin Zhang, Jian Sun, Ning Lin

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Haidi FanFrom the Department of Clinical Laboratory (Fan, Liu, Sun), Branch Hospital of Huai'an First People's Hospital; from the Department of Otolaryngology (Zhang); and from the Department of Clinical Laboratory (Lin), the Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Jiangsu, China.
Yanqiu LiuFrom the Department of Clinical Laboratory (Fan, Liu, Sun), Branch Hospital of Huai'an First People's Hospital; from the Department of Otolaryngology (Zhang); and from the Department of Clinical Laboratory (Lin), the Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Jiangsu, China.
Xin ZhangFrom the Department of Clinical Laboratory (Fan, Liu, Sun), Branch Hospital of Huai'an First People's Hospital; from the Department of Otolaryngology (Zhang); and from the Department of Clinical Laboratory (Lin), the Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Jiangsu, China.
Jian SunFrom the Department of Clinical Laboratory (Fan, Liu, Sun), Branch Hospital of Huai'an First People's Hospital; from the Department of Otolaryngology (Zhang); and from the Department of Clinical Laboratory (Lin), the Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Jiangsu, China.
Ning LinFrom the Department of Clinical Laboratory (Fan, Liu, Sun), Branch Hospital of Huai'an First People's Hospital; from the Department of Otolaryngology (Zhang); and from the Department of Clinical Laboratory (Lin), the Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Jiangsu, China.ORCID https://orcid.org/0000-0001-9573-7811
Xuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the serum concentrations of soluble T-cell immunoglobulin and mucin domain 1 (sTIM-1) and soluble P-selectin (sP-selectin) in individuals who had obstructive sleep apnea-hypopnea syndrome (OSAHS).

methodsBetween December 2020 and November 2022, 134 participants from the Sleep Monitoring Center of the Branch Hospital of Huai'an First People's Hospital, Jiangsu, China, engaged in this cross-sectional study. Participants were categorized as mild OSAHS (n=19), moderate OSAHS (n=22), severe OSAHS (n=57), and non-OSAHS (n=36) groups. Serum levels of sTIM-1, sP-selectin, and interleukin (IL)-6, as well as baseline clinical characteristics and polysomnography outcomes were assessed in each participant.

resultsCompared to the non-OSAHS group, sTIM-1 and sP-selectin levels were considerably elevated in people who had moderate or severe OSAHS (all

conclusionPeople with moderate or severe OSAHS had higher serum sTIM-1 and sP-selectin levels, and elevated sTIM-1 is an independently related factor for OSAHS.

Indexed as

P-SelectinSleep Apnea, ObstructiveCell Cycle ProteinsClinical RelevanceCross-Sectional StudiesHumansImmunoglobulinsIntracellular Signaling Peptides and ProteinsT-LymphocytesCell Cycle ProteinsImmunoglobulinsIntracellular Signaling Peptides and ProteinsP-SelectinSELP protein, humanTIMELESS protein, humanobstructiveP-selectinsleep apneaT-cell immunoglobulin and mucin domain 1

Identifiers

PMID37926453
PMCPMC10712773
OpenAlexW4388383319

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.