Evidence map›Paper›PMID 37926448›Full record

ArticleSaudi medical journal2023

Prognostic value of neutrophil to lymphocyte ratio and platelet counts during chemotherapy in patients with advanced gastric cancer.

Bo Li, Kemeng Wang, Shuai Shi, Meng Li, Min-Ting Ma, Zhi-Guo Zhou, Zhi-Cong Wang, Ya-Ning Gong, Yajie Xiao, Liyan Zhao and 2 more

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Article in Saudi medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

Evaluating the "PLT Clumps?" Flag Originating From Different Channels of the Sysmex XN Haematology Analyser: A Method for Rapidly Distinguishing Between Two Preanalytical Factors Affecting PLT Counting for Cancer Patients.Journal of clinical laboratory analysis · 2025
Article
Can inflammatory indices predict myringosclerosis?Saudi medical journal · 2025
Article
The heterogeneous roles of neutrophils in gastric cancer: scaffold or target?Cellular & molecular biology letters · 2025
Review

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5 · Who and what money

Authors and funding

12 authors.

Bo LiFrom the Department Radiology (B. Li); from the Department of Medical Oncology (Ma, Liu), Fourth Hospital of Hebei Medical University, from the Department of Internal Medicine (K. Wang); from the Department of Orthopedics (Meng); from the Department of Medical Oncology (Gong), the first affiliated Hospital of Xingtai Medical College, from the Department of Medical Oncology (M. Li), Quyang cancer hospital/Hengzhou hospital, from the Department of Radiotherapy (Z. Wang), Cangzhou Central Hospital, Hebei, from YuceBio Technology Co. Ltd. (Xiao), Guangdong, China, and from the Department of Pathology (Shi), GROW-School for Oncology & Developmental Biology, Maastricht University, Maastricht, The Netherlands.ORCID https://orcid.org/0000-0001-5406-5799

Kemeng WangFrom the Department Radiology (B. Li); from the Department of Medical Oncology (Ma, Liu), Fourth Hospital of Hebei Medical University, from the Department of Internal Medicine (K. Wang); from the Department of Orthopedics (Meng); from the Department of Medical Oncology (Gong), the first affiliated Hospital of Xingtai Medical College, from the Department of Medical Oncology (M. Li), Quyang cancer hospital/Hengzhou hospital, from the Department of Radiotherapy (Z. Wang), Cangzhou Central Hospital, Hebei, from YuceBio Technology Co. Ltd. (Xiao), Guangdong, China, and from the Department of Pathology (Shi), GROW-School for Oncology & Developmental Biology, Maastricht University, Maastricht, The Netherlands.

Shuai ShiFrom the Department Radiology (B. Li); from the Department of Medical Oncology (Ma, Liu), Fourth Hospital of Hebei Medical University, from the Department of Internal Medicine (K. Wang); from the Department of Orthopedics (Meng); from the Department of Medical Oncology (Gong), the first affiliated Hospital of Xingtai Medical College, from the Department of Medical Oncology (M. Li), Quyang cancer hospital/Hengzhou hospital, from the Department of Radiotherapy (Z. Wang), Cangzhou Central Hospital, Hebei, from YuceBio Technology Co. Ltd. (Xiao), Guangdong, China, and from the Department of Pathology (Shi), GROW-School for Oncology & Developmental Biology, Maastricht University, Maastricht, The Netherlands.

Meng LiFrom the Department Radiology (B. Li); from the Department of Medical Oncology (Ma, Liu), Fourth Hospital of Hebei Medical University, from the Department of Internal Medicine (K. Wang); from the Department of Orthopedics (Meng); from the Department of Medical Oncology (Gong), the first affiliated Hospital of Xingtai Medical College, from the Department of Medical Oncology (M. Li), Quyang cancer hospital/Hengzhou hospital, from the Department of Radiotherapy (Z. Wang), Cangzhou Central Hospital, Hebei, from YuceBio Technology Co. Ltd. (Xiao), Guangdong, China, and from the Department of Pathology (Shi), GROW-School for Oncology & Developmental Biology, Maastricht University, Maastricht, The Netherlands.

Min-Ting MaFrom the Department Radiology (B. Li); from the Department of Medical Oncology (Ma, Liu), Fourth Hospital of Hebei Medical University, from the Department of Internal Medicine (K. Wang); from the Department of Orthopedics (Meng); from the Department of Medical Oncology (Gong), the first affiliated Hospital of Xingtai Medical College, from the Department of Medical Oncology (M. Li), Quyang cancer hospital/Hengzhou hospital, from the Department of Radiotherapy (Z. Wang), Cangzhou Central Hospital, Hebei, from YuceBio Technology Co. Ltd. (Xiao), Guangdong, China, and from the Department of Pathology (Shi), GROW-School for Oncology & Developmental Biology, Maastricht University, Maastricht, The Netherlands.

Zhi-Guo ZhouFrom the Department Radiology (B. Li); from the Department of Medical Oncology (Ma, Liu), Fourth Hospital of Hebei Medical University, from the Department of Internal Medicine (K. Wang); from the Department of Orthopedics (Meng); from the Department of Medical Oncology (Gong), the first affiliated Hospital of Xingtai Medical College, from the Department of Medical Oncology (M. Li), Quyang cancer hospital/Hengzhou hospital, from the Department of Radiotherapy (Z. Wang), Cangzhou Central Hospital, Hebei, from YuceBio Technology Co. Ltd. (Xiao), Guangdong, China, and from the Department of Pathology (Shi), GROW-School for Oncology & Developmental Biology, Maastricht University, Maastricht, The Netherlands.

Zhi-Cong WangFrom the Department Radiology (B. Li); from the Department of Medical Oncology (Ma, Liu), Fourth Hospital of Hebei Medical University, from the Department of Internal Medicine (K. Wang); from the Department of Orthopedics (Meng); from the Department of Medical Oncology (Gong), the first affiliated Hospital of Xingtai Medical College, from the Department of Medical Oncology (M. Li), Quyang cancer hospital/Hengzhou hospital, from the Department of Radiotherapy (Z. Wang), Cangzhou Central Hospital, Hebei, from YuceBio Technology Co. Ltd. (Xiao), Guangdong, China, and from the Department of Pathology (Shi), GROW-School for Oncology & Developmental Biology, Maastricht University, Maastricht, The Netherlands.

Ya-Ning GongFrom the Department Radiology (B. Li); from the Department of Medical Oncology (Ma, Liu), Fourth Hospital of Hebei Medical University, from the Department of Internal Medicine (K. Wang); from the Department of Orthopedics (Meng); from the Department of Medical Oncology (Gong), the first affiliated Hospital of Xingtai Medical College, from the Department of Medical Oncology (M. Li), Quyang cancer hospital/Hengzhou hospital, from the Department of Radiotherapy (Z. Wang), Cangzhou Central Hospital, Hebei, from YuceBio Technology Co. Ltd. (Xiao), Guangdong, China, and from the Department of Pathology (Shi), GROW-School for Oncology & Developmental Biology, Maastricht University, Maastricht, The Netherlands.

Yajie XiaoFrom the Department Radiology (B. Li); from the Department of Medical Oncology (Ma, Liu), Fourth Hospital of Hebei Medical University, from the Department of Internal Medicine (K. Wang); from the Department of Orthopedics (Meng); from the Department of Medical Oncology (Gong), the first affiliated Hospital of Xingtai Medical College, from the Department of Medical Oncology (M. Li), Quyang cancer hospital/Hengzhou hospital, from the Department of Radiotherapy (Z. Wang), Cangzhou Central Hospital, Hebei, from YuceBio Technology Co. Ltd. (Xiao), Guangdong, China, and from the Department of Pathology (Shi), GROW-School for Oncology & Developmental Biology, Maastricht University, Maastricht, The Netherlands.

Liyan ZhaoFrom the Department Radiology (B. Li); from the Department of Medical Oncology (Ma, Liu), Fourth Hospital of Hebei Medical University, from the Department of Internal Medicine (K. Wang); from the Department of Orthopedics (Meng); from the Department of Medical Oncology (Gong), the first affiliated Hospital of Xingtai Medical College, from the Department of Medical Oncology (M. Li), Quyang cancer hospital/Hengzhou hospital, from the Department of Radiotherapy (Z. Wang), Cangzhou Central Hospital, Hebei, from YuceBio Technology Co. Ltd. (Xiao), Guangdong, China, and from the Department of Pathology (Shi), GROW-School for Oncology & Developmental Biology, Maastricht University, Maastricht, The Netherlands.

Qingju MengFrom the Department Radiology (B. Li); from the Department of Medical Oncology (Ma, Liu), Fourth Hospital of Hebei Medical University, from the Department of Internal Medicine (K. Wang); from the Department of Orthopedics (Meng); from the Department of Medical Oncology (Gong), the first affiliated Hospital of Xingtai Medical College, from the Department of Medical Oncology (M. Li), Quyang cancer hospital/Hengzhou hospital, from the Department of Radiotherapy (Z. Wang), Cangzhou Central Hospital, Hebei, from YuceBio Technology Co. Ltd. (Xiao), Guangdong, China, and from the Department of Pathology (Shi), GROW-School for Oncology & Developmental Biology, Maastricht University, Maastricht, The Netherlands.

Yi-Bing LiuFrom the Department Radiology (B. Li); from the Department of Medical Oncology (Ma, Liu), Fourth Hospital of Hebei Medical University, from the Department of Internal Medicine (K. Wang); from the Department of Orthopedics (Meng); from the Department of Medical Oncology (Gong), the first affiliated Hospital of Xingtai Medical College, from the Department of Medical Oncology (M. Li), Quyang cancer hospital/Hengzhou hospital, from the Department of Radiotherapy (Z. Wang), Cangzhou Central Hospital, Hebei, from YuceBio Technology Co. Ltd. (Xiao), Guangdong, China, and from the Department of Pathology (Shi), GROW-School for Oncology & Developmental Biology, Maastricht University, Maastricht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the predictive significance of dynamic changes in the neutrophil to lymphocyte ratio (NLR) and platelet counts (PLTs) in patients with advanced gastric cancer (GC) during chemotherapy.

methodsA total of 259 advanced GC patients receiving chemotherapy were enrolled and grouped by high or low NLR with a cut value of 2.5 and PLT with cut value of 300×10

resultsHigher pre-chemotherapy NLR exhibited an association with metastasis and advanced grade of Borrmann type, and higher NLR of pre- or post-chemotherapy GC patients was related with Borrmann type grade. Moreover, higher PLT counts are associated with advanced grades of Borrmann type. Interestingly, patients with lower post-chemotherapy NLR or decreasing NLR hold better overall response rate and disease control rate than those with higher NLR or increasing NLR. Furthermore, patients with high post-chemotherapy NLR alone or higher post-chemotherapy NLR plus higher post-chemotherapy PLT.

conclusionOur study suggested that high post-chemotherapy NLR and post-chemotherapy PLT might be adverse prognostic markers in advanced GC patients undergoing chemotherapy.

Indexed as

NeutrophilsStomach NeoplasmsBlood PlateletsHumansKaplan-Meier EstimateLymphocytesPlatelet CountPrognosischemotherapylymphocytesneutrophilsplatelets (PLTs)stomach neoplasms

Identifiers

PMID37926448

DOI10.15537/smj.2023.44.11.20220946

PMCPMC10712764

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