Evidence map›Paper›PMID 37925559›Full record

Observational studyEye (London, England)2024

Gender differences in central serous chorioretinopathy based on the new multimodal imaging classification.

Niroj Kumar Sahoo, Joshua Ong, Amrish Selvam, Richard Brown, Milana Avdalimov, Ashwini Kulkarni, Saarang Hansraj, Ramkailash Gujar, Marco Lupidi, Dinah Zur and 1 more

Open access · greenAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Niroj Kumar SahooAnant Bajaj retina Institute, Kode Venkatadri Chowdary Campus, L V Prasad Eye Institute, Vijayawada, India.ORCID 0000-0003-0011-2507
Joshua OngUPMC Eye Centre, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Amrish SelvamUPMC Eye Centre, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Richard BrownUPMC Eye Centre, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Milana AvdalimovDivision of Ophthalmology, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Ashwini KulkarniAnant Bajaj retina Institute, Kode Venkatadri Chowdary Campus, L V Prasad Eye Institute, Vijayawada, India.
Saarang HansrajAnant Bajaj retina Institute, Kallam Anji Reddy campus, L V Prasad Eye Institute, Hyderabad, India.
Ramkailash GujarCasey Eye Institute, Oregon Health and Science University, Portland, OR, USA.
Marco LupidiDepartment of Medicine and Surgery, Section of Ophthalmology, University of Perugia, S. Maria Della Misericordia Hospital, 06156, Perugia, Italy.ORCID 0000-0002-6817-2488
Dinah ZurDivision of Ophthalmology, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.ORCID 0000-0003-1147-444X
Jay ChhablaniUPMC Eye Centre, University of Pittsburgh, Pittsburgh, PA, 15213, USA. jay.chhablani@gmail.com.ORCID 0000-0003-1772-3558
University of Pittsburgh · USL V Prasad Eye Institute · INTel Aviv University · ILOregon Health & Science University · USUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo analyse the gender-specific differences in central serous chorioretinopathy (CSCR) based on a new multimodal imaging classification system.

methodThis was a retrospective, multicentric, longitudinal, observational study in patients with a diagnosis of unilateral or bilateral CSCR. Visual acuity outcomes and differences based on 'Simple' and 'Complex' CSCR were analysed. The occurrence of choroidal neovascularization (CNVM) and number of recurrences were also compared. Regression analysis was used to evaluate baseline predictors of final visual acuity.

resultsThe study included 109 eyes of 58 patients (55 eyes of 28 female patients and 54 eyes of 30 male patients). Simple CSCR was seen in 8 (14.8%) eyes and 21 (38.2%) eyes in male and female groups respectively, while complex CSCR was seen in 46 (85.2%) eyes and 34 (61.8%) eyes in male and female groups respectively (p = 0.005). Recurrence was more commonly seen in males (34 eyes) than in females (23 eyes) (p = 0.03). Males (96.7%) were also significantly more likely to have a bilateral presentation (78.6% in females) (p = 0.03). Conversely, CNVM was more commonly seen in female eyes (8 eyes) than male eyes (4 eyes) (p = 0.23). On multivariable regression analysis, factors affecting reduced need for treatment were history of steroid use, good visual acuity at baseline, and simple CSCR. Factors affecting good final visual acuity were history of steroid use, good visual acuity at baseline, and younger age.

conclusionMales tended to have complex CSCR and recurrence compared to the female sub-group, while females exhibited CNVM more commonly than males.

Indexed as

Central Serous ChorioretinopathyChoroidal NeovascularizationFemaleFluorescein AngiographyHumansMaleRetrospective StudiesSex FactorsSteroidsTomography, Optical CoherenceSteroids

Identifiers

PMID37925559
PMCPMC10966035
OpenAlexW4388339747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.