ArticleNature communications2023
Petal size is controlled by the MYB73/TPL/HDA19-miR159-CKX6 module regulating cytokinin catabolism in Rosa hybrida.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 58 citations in OpenAlex.
- Histone deacetylation links jasmonic acid signaling to flower size control in rose.Molecular horticulture · 2026Article
- The miR5021-WRKY28-CHS3 Module Regulates Anthocyanin Biosynthesis and Resistance to Anthracnose in Camellia oleifera Peel.Plant, cell & environment · 2026Article
- A review of ARGOS-mediated regulation of plant organ size: molecular mechanisms, environmental interactions, and agricultural implications.Functional & integrative genomics · 2026Review
- PsGA2ox2 is a novel target of miR159 involved in endodormancy regulation in tree peony (Paeonia suffruticosa).Molecular horticulture · 2026Article
- The miR319/bHLH094 Module Regulates Creeping Bentgrass Thermotolerance by Modulating Auxin Biosynthesis and Signalling Pathway.Plant biotechnology journal · 2026Article
- Brachypodium HISTONE DEACETYLASE 19.1 promotes yield, flowering, and freezing tolerance at the expense of drought tolerance.BMC plant biology · 2026Article
- Genome-wide reprogramming of sRNA and lncRNA in the epigenetic regulation following interspecific hybridization in the Brassica species.Molecular horticulture · 2026Article
- Comparative Transcriptomics Analysis Reveals Genes Associated with a Dehiscent-Corolla Mutant in Sesame (International journal of molecular sciences · 2025Article
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- Heterometric expression of an LBD gene via LBD-TCP assembly regulates floral organ size and fruit weight in Physalis.Horticulture research · 2025Article
- Genome-Wide Identification, Drought-Responsive Expression, and EAR-Mediated Regulatory Network Construction ofPlants (Basel, Switzerland) · 2025Article
- Genomic signatures of adaptation in seed traits in the wild plant Brassica incana.Communications biology · 2025Article
- The GAs-RhMYB70 feedback loop fine-tunes cell expansion and petal size by modulating cellulose content in rose.Horticulture research · 2025Article
- Sizing up beauty: Mechanisms of petal size regulation in ornamental plants.Plant physiology · 2025Review
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- Transcriptome analysis reveals the mechanisms underlying petal growth during the flower opening process in Phalaenopsis orchids.BMC plant biology · 2025Article
- Building beauty: Understanding how hormone signaling regulates petal patterning and morphogenesis.The Plant journal : for cell and molecular biology · 2025Review
- Genome-wide identification of WOX family members in rose and functional analysis of RcWUS1 in embryogenic transformation.The plant genome · 2025Article
- Article
- Phase separation of MYB73 regulates seed oil biosynthesis in Arabidopsis.Plant physiology · 2025Article
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The size of plant lateral organs is determined by well-coordinated cell proliferation and cell expansion. Here, we report that miR159, an evolutionarily conserved microRNA, plays an essential role in regulating cell division in rose (Rosa hybrida) petals by modulating cytokinin catabolism. We uncover that Cytokinin Oxidase/Dehydrogenase6 (CKX6) is a target of miR159 in petals. Knocking down miR159 levels results in the accumulation of CKX6 transcripts and earlier cytokinin clearance, leading to a shortened cell division period and smaller petals. Conversely, knocking down CKX6 causes cytokinin accumulation and a prolonged developmental cell division period, mimicking the effects of exogenous cytokinin application. MYB73, a R2R3-type MYB transcription repressor, recruits a co-repressor (TOPLESS) and a histone deacetylase (HDA19) to form a suppression complex, which regulates MIR159 expression by modulating histone H3 lysine 9 acetylation levels at the MIR159 promoter. Our work sheds light on mechanisms for ensuring the correct timing of the exit from the cell division phase and thus organ size regulation by controlling cytokinin catabolism.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.