Evidence map›Paper›PMID 37925453›Full record

ArticleNature communications2023

Daily rhythm in cortical chloride homeostasis underpins functional changes in visual cortex excitability.

Enrico Pracucci, Robert T Graham, Laura Alberio, Gabriele Nardi, Olga Cozzolino, Vinoshene Pillai, Giacomo Pasquini, Luciano Saieva, Darren Walsh, Silvia Landi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  16. Bidirectional Regulation of GABALife (Basel, Switzerland) · 2024
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Enrico Pracucci *National Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze, Consiglio Nazionale delle Ricerche (CNR) and Scuola Normale Superiore Pisa, 56127, Pisa, Italy.ORCID 0000-0002-2185-4510
Robert T Graham *Newcastle University Biosciences Institute, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.
Laura Alberio *Newcastle University Biosciences Institute, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.ORCID 0000-0002-2887-3343
Gabriele Nardi *National Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze, Consiglio Nazionale delle Ricerche (CNR) and Scuola Normale Superiore Pisa, 56127, Pisa, Italy.ORCID 0000-0003-0475-2771
Olga CozzolinoNational Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze, Consiglio Nazionale delle Ricerche (CNR) and Scuola Normale Superiore Pisa, 56127, Pisa, Italy.
Vinoshene PillaiNational Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze, Consiglio Nazionale delle Ricerche (CNR) and Scuola Normale Superiore Pisa, 56127, Pisa, Italy.ORCID 0000-0001-7350-3969
Giacomo PasquiniNational Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze, Consiglio Nazionale delle Ricerche (CNR) and Scuola Normale Superiore Pisa, 56127, Pisa, Italy.ORCID 0000-0003-3894-7649
Luciano SaievaNewcastle University Biosciences Institute, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.
Darren WalshNewcastle University Biosciences Institute, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.ORCID 0000-0002-8010-8067
Silvia LandiInstitute of Neuroscience CNR, Pisa, Italy.ORCID 0000-0001-7999-3452
Jinwei ZhangInstitute of Biomedical and Clinical Sciences, Medical School, College of Medicine and Institute of Health, University of Exeter, Hatherly Laboratories, Exeter, EX4 4PS, UK.ORCID 0000-0001-8683-509X
Andrew J TrevelyanNewcastle University Biosciences Institute, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK. andrew.trevelyan@newcastle.ac.uk.ORCID 0000-0001-9307-4241
Gian-Michele RattoNational Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze, Consiglio Nazionale delle Ricerche (CNR) and Scuola Normale Superiore Pisa, 56127, Pisa, Italy. gianmichele.ratto@sns.it.ORCID 0000-0001-9632-7769
Istituto Nanoscienze · ITNewcastle University · GBChinese Academy of Sciences · CNUniversity of Padua · IT

Funding

Medical Research Council MR/R005427/1
6 · The paper itself

Abstract

Cortical activity patterns are strongly modulated by fast synaptic inhibition mediated through ionotropic, chloride-conducting receptors. Consequently, chloride homeostasis is ideally placed to regulate activity. We therefore investigated the stability of baseline [Cl

Indexed as

SymportersVisual CortexAnimalsChloridesHomeostasisMicePyramidal CellsChloridesSymporters

Identifiers

PMID37925453
PMCPMC10625537
OpenAlexW4388338188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.