Evidence map›Paper›PMID 37925424›Full record

ArticleNature communications2023

c-Myc uses Cul4b to preserve genome integrity and promote antiviral CD8

Asif A Dar, Dale D Kim, Scott M Gordon, Kathleen Klinzing, Siera Rosen, Ipsita Guha, Nadia Porter, Yohaniz Ortega, Katherine S Forsyth, Jennifer Roof and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Asif A DarDivision of Protective Immunity, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. dara@chop.edu.ORCID 0000-0002-0060-6200
Dale D KimDivision of Protective Immunity, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0003-1987-3680
Scott M GordonDivision of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0003-1028-1953
Kathleen KlinzingDivision of Protective Immunity, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0002-3220-4783
Siera RosenDivision of Protective Immunity, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Ipsita GuhaDivision of Protective Immunity, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Nadia PorterDivision of Protective Immunity, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Yohaniz OrtegaDivision of Protective Immunity, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Katherine S ForsythDivision of Protective Immunity, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0002-4991-1601
Jennifer RoofDivision of Cell Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0003-3852-1330
Hossein FazeliniaDivision of Cell Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Lynn A SpruceDivision of Cell Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0001-9640-9158
Laurence C EisenlohrDivision of Protective Immunity, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0002-8475-7910
Edward M BehrensDivision of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Paula M OliverDivision of Protective Immunity, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. paulao@pennmedicine.upenn.edu.ORCID 0000-0002-0455-3767
Children's Hospital of Philadelphia · US

Funding

HEMATOPOIESIS TRAINING GRANTT32DK007780 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI TONG, WEI · 1999 to 2023
$6.7M
Graduate Training in Developmental BiologyT32HD083185 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI Michael Granato, Foteini Mourkioti · 2015 to 2026
$4.0M
A Cul5 E3 ubiquitin ligase complex that prevents allergic asthmaR01AI148240 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI OLIVER, PAULA MARIA · 2020 to 2024
$2.7M
NIAID NIH HHS R01 AI148240NICHD NIH HHS T32 HD083185NIDDK NIH HHS T32 DK007780
6 · The paper itself

Abstract

During infection, virus-specific CD8

Indexed as

CD8-Positive T-LymphocytesCullin ProteinsLymphocytic choriomeningitis virusProto-Oncogene Proteins c-mycCell CycleUbiquitin-Protein LigasesCullin ProteinsProto-Oncogene Proteins c-mycUbiquitin-Protein Ligases

Identifiers

PMID37925424
PMCPMC10625626
OpenAlexW4388339428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.