Evidence map›Paper›PMID 37924978›Full record

ArticleJournal of lipid research2023

Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid families.

Brian A Kleiboeker, Cheryl Frankfater, Mary E Davey, Fong-Fu Hsu

Abstract read
In one paragraph

Article in Journal of lipid research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Characterization ofJournal of the American Society for Mass Spectrometry · 2025
    Article
  3. Review
  4. Article
  5. mBio · 2024
    Article
  6. The multifaceted role of c-di-AMP signaling in the regulation ofFrontiers in cellular and infection microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brian A KleiboekerMass Spectrometry Resource, Division of Endocrinology, Metabolism, and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Cheryl FrankfaterMass Spectrometry Resource, Division of Endocrinology, Metabolism, and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Mary E DaveyDepartment of Microbiology, The Forsyth Institute, Cambridge, MA, USA.
Fong-Fu HsuMass Spectrometry Resource, Division of Endocrinology, Metabolism, and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: fhsu@wustl.edu.

Funding

Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
TrainingP41GM103422 · NIGMS · WASHINGTON UNIVERSITY · PI YARASHESKI, KEVIN E · 2012 to 2019
$12.0M
Regulatory Mechanisms Controlling Expression of P. gingivalis Surface StructuresR01DE019117 · NIDCR · UNIVERSITY OF FLORIDA · PI DAVEY, MARY ELLEN · 2009 to 2019
$4.5M
Microbial sphingolipids and suppression of host inflammation in periodontal diseaseR01DE031159 · NIDCR · UNIVERSITY OF FLORIDA · PI DAVEY, MARY ELLEN, GIBSON, FRANK C · 2021 to 2025
$2.9M
NIDCR NIH HHS R01 DE019117NIDCR NIH HHS R01 DE031159NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK056341NIGMS NIH HHS P41 GM103422
6 · The paper itself

Abstract

Porphyromonas gingivalis, like other members of the phylum Bacteroidetes (synonym Bacteroidota), synthesizes several classes of dihydroceramides and peptidolipids. Using a similar strategy as that recently used to delimit the lipidome of its close relative Bacteroides fragilis, we applied linear ion trap multiple-stage mass spectrometry (linear ion trap MS

Indexed as

GlycerolPorphyromonas gingivalisCeramidesLipidomicsCeramidesdihydroceramideGlycerolbacterial lipidsbisphosphorylceramide glycerollipidomicspeptidolipidssphingolipidstandem mass spectrometry

Identifiers

PMID37924978
PMCPMC10757044

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.