Evidence map›Paper›PMID 37924781›Full record

ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2023

Basilar artery bifurcation anatomy as a determinant of recanalization and stroke outcome: Basilar artery bifurcation anatomy and stroke outcome.

Mohammad Hossein Abbasi, Ali Eltatawy, Steven R Messé, Ashkan Mowla, Charles J Prestigiacomo, Matthew S Smith, Michela Rosso, Scott E Kasner, Peyman Shirani

Open access · greenAbstract read
In one paragraph

Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Comparison of ischemic and hemorrhagic stroke in the thalamus.Quantitative imaging in medicine and surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mohammad Hossein AbbasiDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
Ali EltatawyDepartment of Neurology, College of Medicine, University of Cincinnati, Cincinnati, OH, USA.
Steven R MesséDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
Ashkan MowlaDepartment of Neurological Surgery, University of Southern California, CA, USA.
Charles J PrestigiacomoDepartment of Neurological Surgery, College of Medicine, University of Cincinnati, Cincinnati, OH, USA.
Matthew S SmithDepartment of Neurology, College of Medicine, University of Cincinnati, Cincinnati, OH, USA.
Michela RossoDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
Scott E KasnerDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: kasner@mail.med.upenn.edu.
Peyman ShiraniDepartment of Neurology, College of Medicine, University of Cincinnati, Cincinnati, OH, USA.
University of Pennsylvania · USUniversity of Cincinnati Medical Center · USNeurological Surgery · USUniversity of Southern California · US

Funding

The Philadelphia Regional Stroke Trials Network Coordinating Center (PRSTNCC)U24NS107224 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Brett Lee Cucchiara · 2018 to 2026
$3.2M
NINDS NIH HHS U24 NS107224
6 · The paper itself

Abstract

objectivesThrombectomy improves outcomes in patients with basilar artery (BA) occlusion. We hypothesized that the anatomic configuration of the BA bifurcation, classified as T- or Y-shaped, may impact the outcome as a T-shaped BA would involve more deep penetrating arteries of the midbrain and thalamus. MATERIALS AND

methodsIn this 2-center retrospective cohort study, we included patients with stroke due to distal BA occlusion and performed blinded classification of their BA distal bifurcation as either T- or Y-shaped. The primary outcomes were favorable outcome at 90-days (modified Rankin Scale 0 - 2) and successful recanalization (TICI scores 2B or 3).

results70 patients (mean age 66 years, 36% women) were included. 38 had T- and 32 had Y-shaped bifurcations. Baseline characteristics were similar for both groups, including demographics, onset to arterial puncture time, baseline NIHSS, THRIVE score, posterior circulation collateral score, and presence of tandem occlusion. Comparing the T- to the Y- shape, there was no difference in the likelihood of successful recanalization (RR: 1.02, CI: [0.86-1.21], p=1.00) nor 90-day favorable mRS (0-2) score (RR: 0.58, CI: [0.25-1.32]; p=0.18). Similarly, mortality at 30 and 90-days were not significantly affected by the type of bifurcation.

conclusionsThe configuration of the basilar artery does not significantly impact on recanalization success or stroke outcome in our study. Further studies are needed to confirm our observations.

Indexed as

Arterial Occlusive DiseasesEndovascular ProceduresStrokeAgedBasilar ArteryFemaleHumansMaleRetrospective StudiesThrombectomyTreatment OutcomeAnatomical variationBasilar arteryBifurcation angleStrokeThrombectomyTICI

Identifiers

PMID37924781
PMCPMC10872429
OpenAlexW4388255445

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.