ReviewCurrent obesity reports2023
Ketogenic Diet: A Nutritional Therapeutic Tool for Lipedema?
Review in Current obesity reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Pooled it
- Molecular Distinctions, Diagnosis, and Mechanism-Based Therapies in Lipedema and Obesity.Current issues in molecular biology · 2026Review
- Current Evidence-Based Clinical Nutritional Approaches in Lipedema: A Scoping Review.Nutrition reviews · 2026Article
- Optimizing Liposuction in Lipedema Patients: A Novel Approach with Perioperative and Intraoperative Ultrasound.Aesthetic plastic surgery · 2026Article
- Postoperative Seroma in Lipedema Surgery: A Retrospective Analysis of 93 Cases from a Single Surgical Team.Aesthetic plastic surgery · 2026Observational
- Lipedema and obesity: A narrative review and treatment protocol.JPRAS open · 2026Review
- The Ketogenic Diet in Type 2 Diabetes and Obesity: A Narrative Review of Clinical Evidence.Nutrients · 2026Review
- Unraveling lipedema: comprehensive insights and the path to future discoveries.npj metabolic health and disease · 2026Review
- Lipedema World Alliance Delphi Consensus-Based Position Paper on the Definition and Management of Lipedema: Results from the 2023 Lipedema World Congress in Potsdam.Nature communications · 2026Article
- Management of lipedema with a biphasic ketogenic/low-carbohydrate diet: a case report.Frontiers in nutrition · 2026Article
- The ketogenic diet alleviates autoimmune thyroiditis caused by Th17/Treg imbalance by inhibiting the HMGB1/NLRP3 signaling pathway.PloS one · 2026Article
- Glucose and insulin dynamics following low-carbohydrate and low-fat diets in females with lipedema and obesity.Frontiers in cell and developmental biology · 2026Article
- The lipedema common case report form as a research tool: standardizing lipedema data collection.Frontiers in global women's health · 2026Article
- The Molecular Mechanisms Underlying Dercum's Disease: Exploring the Intersection of Obesity, Pain, and Inflammation.International journal of molecular sciences · 2025Review
- Nutritional Approaches and Supplementation in Lipedema Management: A Narrative Review of Current Evidence.Current nutrition reports · 2025Review
- Exploring the Anti-Inflammatory Potential of a Mediterranean-Style Ketogenic Diet in Women with Lipedema.Nutrients · 2025Article
- Combined effects of dietary inflammatory index and vigorous physical activity on abdominal adipose tissue: analysis of NHANES 2011-2018.Journal of health, population, and nutrition · 2025Article
- A Case Series on the Efficacy of the Pharmacological Treatment of Lipedema: The Italian Experience with Exenatide.Clinics and practice · 2025Article
- Examining the characteristic features of lipedema and the usefulness of BMI and WHtR in clinical evaluation.BMC women's health · 2025Article
- Therapeutic Applications of Ketogenic Diets in Lipedema: A Narrative Review of Current Evidence.Current obesity reports · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewThis review aims to provide an overview of the current evidence on the efficacy, also considering the anti-inflammatory properties and safety of very low-calorie ketogenic diet (VLCKD) as a potential treatment for lipedema, particularly in the context of obesity. RECENT
findingsLipedema is a chronic disease characterized by abnormal and painful fat buildup on the legs and/or arms. It is often misdiagnosed as obesity or lymphedema. However, although lipedema and obesity can coexist, unlike obesity, lipedema usually affects the legs and thighs without affecting the feet or hands, and the abnormal deposition of adipose tissue in lipedema is painful. The current lifestyle interventions are often unsuccessful in the management of lipedema. There is no consensus on the most effective nutritional approach for managing lipedema. Recent studies have suggested that VLCKD may be an effective treatment for lipedema, demonstrating that it is also superior to other nutritional approaches such as Mediterranean diet or intermittent fasting. Lipedema is a chronic and debilitating disease characterized by abnormal and painful accumulation of adipose tissue in the legs. VLCKD has been shown to be an effective treatment for lipedema, especially in the context of obesity, due to its anti-inflammatory properties. However, further research is needed to determine the long-term safety and efficacy of VLCKD as a treatment for lipedema.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.