ReviewGlobal spine journal2024
A Systematic Review and Meta-Analysis of Vertebral Artery Injury After Cervical Spine Trauma.
Review in Global spine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Traumatic vertebral artery occlusion is associated with high rates of recanalization: insights from a systematic review and meta-analysis.Neurosurgical review · 2025Pooled it
- The Arrow and the Atlas-A Narrow Escape in the Cervical Spine: A Case Report About Penetrating Injury With an Arrow Impacted in the Neck.Clinical case reports · 2026Article
- Vertebral artery dissection and homonymous hemianopsia after a cervical spine fracture in a polytrauma patient with hypoplastic contralateral vertebral artery: a case report.Journal of trauma and injury · 2026Article
- Proximal and distal endovascular embolization of a penetrating V3 vertebral artery transection with adjunctive surgical ligation: A case report.Surgical neurology international · 2026Article
- Accuracy and safety of navigated pedicle screw insertion in cervical spine fractures.Frontiers in surgery · 2026Article
- Epidemiology and Screening of Traumatic Vertebral Artery Injuries at a Large Scandinavian Level 1 Trauma Center.Neurospine · 2025Article
- A unique management strategy to bilateral vertebral artery occlusion following cervical trauma: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Traumatic Vertebral Artery Injury: Diagnosis, Natural History, and Key Considerations for Management.Journal of clinical medicine · 2025Review
- [Which diagnostic tests are indicated in the emergency department after trauma to the cervical spine?]Unfallchirurgie (Heidelberg, Germany) · 2025Review
- Change in management for digital subtraction angiography-identified false-positive traumatic vertebral artery injury.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Covered stent salvage for iatrogenic vertebral artery injury in traumatic cervical spine injury: A case report and literature review.BioMedicine · 2025Article
- Clinical characteristics and outcomes of patients with concomitant cervical spine trauma and vertebral artery injury: A literature review and retrospective analysis.Journal of craniovertebral junction & spineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designSystematic Review and Meta-Analysis.
objectiveIdentify the incidence, mechanism of injury, investigations, management, and outcomes of Vertebral Artery Injury (VAI) after cervical spine trauma.
methodsA systematic review and meta-analysis were conducted in accordance with the PRISMA guidelines (PROSPERO-ID CRD42021295265). Three databases were searched (PubMed, SCOPUS, Google Scholar, CINAHL PLUS). Incidence of VAI, investigations to diagnose (Computed Tomography Angiography, Digital Subtraction Angiography, Magnetic Resonance Angiography), stroke incidence, and management paradigms (conservative, antiplatelets, anticoagulants, surgical, endovascular treatment) were delineated. Incidence was calculated using pooled proportions random effects meta-analysis.
resultsA total of 44 studies were included (1777 patients). 20-studies (n = 503) included data on trauma type; 75.5% (n = 380) suffered blunt trauma and 24.5% (n = 123) penetrating. The overall incidence of VAI was .95% (95% CI 0.65-1.29). From the 16 studies which reported data on outcomes, 8.87% (95% CI 5.34- 12.99) of patients with VAI had a posterior stroke. Of the 33 studies with investigation data, 91.7% (2929/3629) underwent diagnostic CTA; 7.5% (242/3629) underwent MRA and 3.0% (98/3629) underwent DSA. Management data from 20 papers (n = 475) showed 17.9% (n = 85) undergoing conservative therapy, anticoagulation in 14.1% (n = 67), antiplatelets in 16.4% (n = 78), combined therapy in 25.5% (n = 121) and the rest (n = 124) managed using surgical and endovascular treatments.
conclusionVAI in cervical spine trauma has an approximate posterior circulation stroke risk of 9%. Optimal management paradigms for the prevention and management of VAI are yet to be standardized and require further research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.