Evidence map›Paper›PMID 37924143›Full record

ArticleCardio-oncology (London, England)2023

Utilization and short-term outcomes of percutaneous left atrial appendage occlusion in patients with cancer.

Yaqi Zhang, Zhuoran Yang, Muhammad U Almani, Raquel Soon-Shiong, Bolun Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardio-oncology (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Left atrial appendage occlusion in patients with cancer.Journal of thrombosis and thrombolysis · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Left Atrial Appendage Occlusion in Cancer-Associated Atrial Fibrillation: Who, When, and How to Manage Antithrombotic Therapy.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Yaqi Zhang *Department of Internal Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, IL, USA. yaqi920928@gmail.com.
Zhuoran YangMount Sinai St Luke's and Mount Sinai West Hospital, New York, NY, USA.
Muhammad U AlmaniEinstein Medical Center Philadelphia, Philadelphia, PA, USA.
Raquel Soon-ShiongDepartment of Internal Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, IL, USA.
Bolun Liu *Mayo Clinic Health System, Mankato, MN, USA.
Einstein Medical Center Philadelphia · USJohn H. Stroger, Jr. Hospital of Cook County · USMayo Clinic Health System · USMount Sinai Hospital · USUniversity of Iowa Hospitals and Clinics · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous left atrial appendage occlusion (LAAO) has been rapidly evolving since FDA's approval in 2015 and has become more of a same-day-discharge procedure. Cancer patient with atrial fibrillation/flutter (AF) population can benefit from the procedure but the in-hospital outcomes and readmission data were rarely studied.

objectivesWe investigated the utilization, in-hospital and readmission outcomes in cancer patients with AF who underwent LAAO.

methodsData were derived from the National Inpatient Sample and National Readmissions Database from 2016 to 2019. Patients with primary diagnosis of AF admitted for LAAO (ICD-10 code 02L73DK) were grouped by cancer as a secondary diagnosis. We assessed in-hospital mortality, length of stay, total hospital charges, and complications. Thirty-day readmission rates were compared.

resultsLAAO was performed in 60,380 patients with AF and 3% were cancer patients. There were no differences in in-hospital mortality and total hospital charges; however, cancer patients tended to have longer hospital stay (1.59 ± 0.11 vs. 1.32 ± 0.02, p = 0.013). Among complications, cancer patients had higher rates in open or percutaneous pericardial drainage (adjusted odds ratio [aOR] 2.38; 95% confidence interval [CI] 1.19-4.76) and major bleeding events (aOR 7.07; 95% CI 1.82-27.38). There was no statistical significance of 30-day readmission rates between patients with and without cancer (10.0% vs. 9.1%, p = 0.34). The most common readmission reason in cancer patients was gastrointestinal bleeding.

conclusionsLAAO is a promising procedure in cancer patients complicated by AF with contraindication to anticoagulation. Readmission rate is comparable between patients with and without cancer.

Indexed as

Atrial fibrillationLeft atrial appendage occlusionNational inpatient sampleNational readmissions databaseThirty-day readmission rate

Identifiers

PMID37924143
PMCPMC10625234
OpenAlexW4388346055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.