ArticleBMC public health2023
The relationship between depression and benign prostatic hyperplasia in middle-aged and elderly men in India: a large-scale population study.
Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07552961 (Evaluating the Feasibility of a Comprehensive Prehabilitation Program for Use in Benign Prostatic Hyperplasia Patients Undergoing Holmium Laser Enucleation of the Prostate), which is not on this map. Cited by 9 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluating the Feasibility of a Comprehensive Prehabilitation Program for Use in Benign Prostatic Hyperplasia Patients Undergoing Holmium Laser Enucleation of the Prostate
Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Finasteride Use Does Not Lead to Depression or Suicide: Insights From a Large-Scale Cohort Study and Mendelian Randomization Analysis.Journal of cosmetic dermatology · 2025Article
- Risk model for depression in patients with chronic prostatitis/chronic pelvic pain syndrome: A retrospective cross-sectional study.The Journal of international medical research · 2025Article
- Research on sleep disorders in patients with mental illness: A review of Indian studies.Indian journal of psychiatry · 2025Review
- Quantifying depression and the risk of chronic liver diseases: results from a large-scale longitudinal cohort study.Frontiers in public health · 2025Article
- Association Between Subclinical Depression and the Severity of Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia and the Mediating Effect of Sleep Quality in Elderly Chinese Men.Neuropsychiatric disease and treatment · 2025Article
- Circulating levels of blood biomarkers and risk of benign prostatic hyperplasia: Results from two large cohorts in Europe and East Asia.Journal of global health · 2024Article
- Correlation between benign prostatic hyperplasia and comorbidities: a systematic analysis integrating global burden of disease and mendelian randomization study.Journal of translational medicine · 2024Article
- Household air pollution and urinary incontinence symptoms among older adults in LASI: a large-scale population-based study.BMC public health · 2024Article
- The association between long-term exposure to ambient PMBMC cardiovascular disorders · 2024Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThere have been few investigations on the association between depression and benign prostatic hyperplasia (BPH). This study aims to explore the correlation between depression and BPH among middle-aged and older men in India.
methodsWe utilized data from male individuals aged 45 years and older who participated in the initial wave (2017-2018) of the Longitudinal Aging Study in India (LASI). The presence of BPH symptoms was based on self-reported information, while depressive symptoms were evaluated using CESD-10. The analysis was a cross-sectional study conducted on a final sample size of 30,108 male participants. To examine associations, we employed multivariate logistic regression analysis along with subgroup analysis and interaction tests.
resultsA total of 439 (1.46%) men reported BPH and had a higher depression score (10.18 ± 4.22 vs. 9.28 ± 4.00). The findings indicated a significant association between the depression score and the likelihood of developing BPH, even after accounting for all potential confounding variables (OR = 1.054, 95% CI: 1.030-1.078, p < 0.00001). The participants were then categorized into a depression group and a normal group based on their CESD-10 score, using a threshold of 10 to ascertain the existence or nonexistence of depression. After adjusting for all variables in model IV, the findings continued to exhibit statistical significance (OR = 1.611, CI: 1.327-1.955, p < 0.00001). Significant interaction effects of age, education level, caste or tribe, and alcohol consumption were observed (p for interaction < 0.05).
conclusionOur research found that BPH was significantly linked to the presence of depressive symptoms among middle-aged and elderly Indian men. Additional prospective research is necessary to clarify this association and investigate potential mechanisms.
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