ArticleScientific reports2023
Effects of heavy metal exposure during pregnancy on birth outcomes.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
- Associations of Pre-Pregnancy and Prenatal Outdoor Nighttime Light, Green Space and Neighbourhood Walkability With Preterm Birth: Results From Ruian Birth Cohort Study.Paediatric and perinatal epidemiology · 2026Article
- Toxic Trace Element Levels in Maternal and Cord Blood Worldwide and Their Impact on Pregnancy: A Narrative Review.Journal of xenobiotics · 2026Review
- Hair metal concentrations in a mother-newborn population from a polluted megacity: an indicator of prenatal metal exposure.Journal of exposure science & environmental epidemiology · 2026Article
- Exposure-associated health implications of potentially toxic elements in maternal and umbilical cord blood at Ishaka adventist hospital, Bushenyi District, Uganda.Scientific reports · 2026Article
- Genetic Modulation of Mercury Exposure on Perinatal and Birth Outcomes: A Systematic Review and Meta-Analysis of Gene-Environment Interactions.Journal of xenobiotics · 2026Review
- Neurotoxicity of heavy metals across the lifespan: The beneficial role of nutrition from fetus to the elderly.Advances in neurotoxicology · 2026Article
- Associations between prenatal metal mixtures and allergic symptoms in childhood.The Science of the total environment · 2025Article
- Prenatal exposure to metals and metal mixtures influences birth weight in affected populations in the Republic of Suriname, South America.Environmental research · 2025Article
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- Mapping Chemical-Gene Interactions for Developmental Lethality and Pregnancy Loss.medRxiv : the preprint server for health sciences · 2025Article
- Metallomic profiles of pregnant women living with obesity in the UK: a secondary analysis of UPBEAT.Metallomics : integrated biometal science · 2025Article
- Association between urinary heavy metal concentrations, thyroid hormones, and birth outcomes among pregnant women in Isfahan City.Scientific reports · 2025Article
- Potentially toxic metals in umbilical cord blood as a biomarker for passive smoker women.Scientific reports · 2025Article
- Prenatal exposure to metal mixture and birth weight; a Bayesian kernel machine regression analysis of two cohort studies in Japan and Iran.Journal of environmental health science & engineering · 2025Article
- Association of maternal metal exposure and psychological status with adverse pregnancy outcomes: a nested case-control study.Frontiers in public health · 2025Article
- Paternal Lead Exposure and Pregnancy Outcomes: A Systematic Review and Meta-Analysis.Environmental health insights · 2025Review
- Development, validation and reliability of scales and items for heat wave risk assessment of pregnant women.International journal of biometeorology · 2024Article
- Enhancing Heavy Metal Detection through Electrochemical Polishing of Carbon Electrodes.Biosensors · 2024Article
Corrections and comments
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Authors and funding
7 authors at 20 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exposure to heavy metals such as lead, cadmium, and mercury poses serious health risks to pregnant women because of their high toxicity. In this study, we investigated the associations of heavy metal exposure with birth outcomes of Korean infants. Data of 5,215 women between 2015 and 2019 were analyzed. This study was part of the Korean Children's Environmental Health (Ko-CHENS) study. Linear regression and logistic regression analyses were used to examine effects of concentrations of lead, cadmium, and mercury on birth weight, small for gestational age, and large for gestational age after adjusting for maternal age groups, parity, infant sex, education, income, smoking, drinking, body mass index, stillbirth, premature birth, diabetes, hypertension, and gestational diabetes. Besides adjusting for these covariates, each metal was mutually adjusted to estimate birth weight and large for gestational age status. Maternal cadmium concentrations during early pregnancy (β = - 39.96; 95% confidence interval (CI): - 63.76, - 16.17) and late pregnancy (β = - 37.24; 95% CI - 61.63, - 12.84) were significantly associated with birth weight. Cadmium levels during early pregnancy (adjusted OR = 0.637; 95% CI 0.444, 0.912) were also associated with large for gestational age status. Our findings suggest that prenatal cadmium exposure, even at a low level of exposure, is significantly associated with low birth weight.
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