Evidence map›Paper›PMID 37923121›Full record

ArticleNeuropharmacology2024

Altered brain serotonin 5-HT

Tanishka S Saraf, Yiming Chen, Richa Tyagi, Clinton E Canal

Open access · greenAbstract read
In one paragraph

Article in Neuropharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Moving beyond 5-HTPsychopharmacology · 2026
    Article
  2. Pharmacologic MRI Brain Imaging Studies of Serotonin 5-HTPharmacology research & perspectives · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tanishka S SarafMercer University, College of Pharmacy, Department of Pharmaceutical Sciences, 3001 Mercer University Drive, Atlanta, GA, 30341, USA.
Yiming ChenMercer University, College of Pharmacy, Department of Pharmaceutical Sciences, 3001 Mercer University Drive, Atlanta, GA, 30341, USA.
Richa TyagiMercer University, College of Pharmacy, Department of Pharmaceutical Sciences, 3001 Mercer University Drive, Atlanta, GA, 30341, USA.
Clinton E CanalMercer University, College of Pharmacy, Department of Pharmaceutical Sciences, 3001 Mercer University Drive, Atlanta, GA, 30341, USA. Electronic address: canal_ce@mercer.edu.
Mercer University Health Sciences Center · USMercer University · US

Funding

Targeting Serotonin 5-HT1A and 5-HT7 Receptors to Prevent Audiogenic Seizures and Correct Translationally Valid EEG Phenotypes in a Juvenile Fmr1 Knock-Out Mouse Model of Fragile X SyndromeR15NS118352 · NINDS · MERCER UNIVERSITY MACON · PI CANAL, CLINTON E · 2020 to 2020
$424k
NINDS NIH HHS R15 NS118352
6 · The paper itself

Abstract

There are no approved pharmacotherapies for fragile X syndrome (FXS), a rare neurodevelopmental disorder caused by a mutation in the FMR1 promoter region that leads to various symptoms, including intellectual disability and auditory hypersensitivity. The gene that encodes inhibitory serotonin 1A receptors (5-HT

Indexed as

Epilepsy, ReflexFragile X SyndromeInferior ColliculiAnimalsFemaleFragile X Messenger Ribonucleoprotein 1MaleMiceMice, KnockoutReceptor, Serotonin, 5-HT1ASerotoninFmr1 protein, mouseFragile X Messenger Ribonucleoprotein 1Htr1a protein, mouseReceptor, Serotonin, 5-HT1ASerotonin5-HT(1A) receptor expression5-HT(1A) receptor functionAudiogenic seizuresFmr1 knockout miceFragile X syndrome

Identifiers

PMID37923121
PMCPMC11426339
OpenAlexW4388283549

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.