Evidence map›Paper›PMID 37922596›Full record

ArticleJournal of psychiatric research2023

Personality characteristics, not clinical symptoms, are associated with anhedonia in a community sample: A preliminary investigation.

Russell H Tobe, Lucia Tu, John R Keefe, Melissa M Breland, Benjamin A Ely, Melissa Sital, Jasmin T Richard, Umit Tural, Dan V Iosifescu, Vilma Gabbay

Open access · greenAbstract read
In one paragraph

Article in Journal of psychiatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Russell H TobeNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA; Center for the Developing Brain, Child Mind Institute, New York, NY, 10022, USA. Electronic address: russell.tobe@nki.rfmh.org.
Lucia TuNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
John R KeefeDepartment of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Melissa M BrelandNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Benjamin A ElyDepartment of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Melissa SitalNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Jasmin T RichardNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA; Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Umit TuralNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA.
Dan V IosifescuNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA; Department of Psychiatry, New York University School of Medicine, New York, NY, 10016, USA.
Vilma GabbayNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, 10962, USA; Department of Psychiatry and Behavioral Sciences, University of Miami Leonard M. Miller School of Medicine, Coral Gables, FL, 33124, USA.
Nathan Kline Institute for Psychiatric Research · USAlbert Einstein College of Medicine · US

Funding

Integrated Care for Chronic Pain and Opioid Use Disorder: The IMPOWR Research Center at Montefiore/Einstein (IMPOWR-ME)RM1DA055437 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI ARNSTEN, JULIA H., GABBAY, VILMA · 2021 to 2025
$13.7M
A Multimodal Parent-focused Intervention for Vulnerable Populations in the BronxR01MH126821 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI ALPERT, JONATHAN EDWARD, GABBAY, VILMA · 2021 to 2025
$4.2M
Biobehavioral Predictors of Illness Progression in Adolescent DepressionR01MH120601 · NIMH · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GABBAY, VILMA · 2020 to 2024
$3.9M
Longitudinal Discovery of Brain Developmental TrajectoriesU01MH099059 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI MILHAM, MICHAEL PETER · 2013 to 2017
$3.7M
The Neuroimmunology of Depression in Women Living With HIVR01MH128878 · NIMH · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GABBAY, VILMA, SHARMA, ANJALI · 2021 to 2025
$3.5M
Inflammation, BBB disruption, and Reward Function in the Pathogenesis of Depression among PWHR01MH131207 · NIMH · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Joan Weinberger Berman, Vilma Gabbay · 2022 to 2026
$3.5M
The Neural Underpinnings of Depression and Cannabis Use in Young PLWHR01DA054885 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Vilma Gabbay, Anjali Sharma · 2021 to 2026
$3.2M
Mapping interindividual variation in the aging connectomeR01AG047596 · NIA · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI COLCOMBE, STAN J, MILHAM, MICHAEL PETER · 2015 to 2019
$3.1M
Discovery Science of Human Brain Function Across the LifespanR01MH094639 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI MILHAM, MICHAEL PETER · 2011 to 2014
$2.7M
Real-time fMRI Neurofeedback Based Stratification of Default Network RegulationR01MH101555 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI CRADDOCK, RICHARD CAMERON · 2013 to 2016
$2.6M
Habenula Developmental Trajectories in the ABCD StudyR21MH126501 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI ELY, BENJAMIN ADAM, GABBAY, VILMA · 2021 to 2022
$462k
NIA NIH HHS R01 AG047596NIDA NIH HHS R01 DA054885NIDA NIH HHS RM1 DA055437NIMH NIH HHS R01 MH094639NIMH NIH HHS R01 MH101555NIMH NIH HHS R01 MH120601NIMH NIH HHS R01 MH126821NIMH NIH HHS R01 MH128878NIMH NIH HHS R01 MH131207NIMH NIH HHS R21 MH126501NIMH NIH HHS U01 MH099059
6 · The paper itself

Abstract

Anhedonia is a salient transdiagnostic psychiatric symptom associated with increased illness severity and chronicity. Anhedonia is also present to varying degrees in non-clinical cohorts. Here, we sought to examine factors influencing expression of anhedonia. Participants (N = 335) were recruited through the Nathan Kline Institute-Rockland Sample, an initiative to deeply phenotype a large community sample across the lifespan. Utilizing a data-driven approach, we evaluated associations between anhedonia severity, indexed by Snaith-Hamilton Pleasure Scale (SHAPS), and 20 physical, developmental, and clinical measures, including Structured Clinical Interview for DSM-IV, Beck Depression Inventory, State-Trait Anxiety Inventory, NEO Five-Factor Inventory-3 (NEO-FFI-3), BMI, Hemoglobin A1C, and demography. Using a bootstrapped AIC-based backward selection algorithm, seven variables were retained in the final model: NEO-FFI-3 agreeableness, extraversion, and openness to experience; BMI; sex; ethnicity; and race. Though median SHAPS scores were greater in participants with psychiatric diagnoses (18.5) than those without (17.0) (U = 12238.5, z = 2.473, p = 0.013), diagnosis and symptom measures were not retained as significant predictors in the final robust linear model. Participants scoring higher on agreeableness, extraversion, and openness to experience reported significantly lower anhedonia. These results demonstrate personality as a mild-to-moderate but significant driver of differences in experiencing pleasure in a community sample.

Indexed as

AnhedoniaPersonalityHumansPersonality DisordersPersonality InventoryPsychiatric Status Rating ScalesAnhedoniaDepressionHealthNEO-FFIPersonalitySHAPS

Identifiers

PMID37922596
PMCPMC11334051
OpenAlexW4388186653

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.