Evidence map›Paper›PMID 37922115›Full record

ArticleAdministration and policy in mental health2024

A Tutorial Introduction to Heterogeneous Treatment Effect Estimation with Meta-learners.

Marie Salditt, Theresa Eckes, Steffen Nestler

Abstract read
In one paragraph

Article in Administration and policy in mental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marie SaldittInstitut für Psychologie, University of Münster, Fliednerstr. 21, 48149, Münster, Germany. msalditt@uni-muenster.de.ORCID 0000-0002-1278-1065
Theresa EckesInstitut für Psychologie, University of Münster, Fliednerstr. 21, 48149, Münster, Germany.ORCID 0000-0001-9704-8198
Steffen NestlerInstitut für Psychologie, University of Münster, Fliednerstr. 21, 48149, Münster, Germany.ORCID 0000-0001-9724-2441

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychotherapy has been proven to be effective on average, though patients respond very differently to treatment. Understanding which characteristics are associated with treatment effect heterogeneity can help to customize therapy to the individual patient. In this tutorial, we describe different meta-learners, which are flexible algorithms that can be used to estimate personalized treatment effects. More specifically, meta-learners decompose treatment effect estimation into multiple prediction tasks, each of which can be solved by any machine learning model. We begin by reviewing necessary assumptions for interpreting the estimated treatment effects as causal, and then give an overview over key concepts of machine learning. Throughout the article, we use an illustrative data example to show how the different meta-learners can be implemented in R. We also point out how current popular practices in psychotherapy research fit into the meta-learning framework. Finally, we show how heterogeneous treatment effects can be analyzed, and point out some challenges in the implementation of meta-learners.

Indexed as

AlgorithmsMachine LearningPsychotherapyHumansTreatment Effect HeterogeneityCausal inferenceIndividual treatment effectsMachine learningMeta-learnersPersonalized medicineTreatment effect heterogeneity

Identifiers

PMID37922115
PMCPMC11379759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.