Evidence map›Paper›PMID 37922055›Full record

ArticleCVIR endovascular2023

Non-target embolic events during prostatic embolization with ethylene vinyl alcohol copolymer (EVOH).

Jacques Sédat, Paolo Arnoffi, Florent Poirier, Modhar Jamjoom, Charles Raffaelli, Frederic Colomb, Yves Chau

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in CVIR endovascular, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05395299 (Feasibility of Prostatic Arterial Embolization With SQUID), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05395299 nacompletednot on this map

Feasibility of Prostatic Arterial Embolization With SQUID (Ethylene Vinyl Alcohol Copolymer ) in Symptomatic Patients With Benign Prostatic Hyperplasia: Monocentric Pilot Study

TypeinterventionalSponsorCentre Hospitalier Universitaire de NiceRan2022 to 2024Enrolled12ConditionsProstatic Hyperplasia, BenignArmsSQUID (Ethylene Vinyl Alcohol Copolymer ) administred to the participant with the intervention Prostatic Arterial Embolization
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jacques SédatService de NeuroInterventionnel, CHU de Nice Hôpital, Pasteur 2, 30 Voie Romaine, Nice, France. jsedat@yahoo.fr.ORCID http://orcid.org/0000-0003-2312-1457
Paolo ArnoffiService de NeuroInterventionnel, CHU de Nice Hôpital, Pasteur 2, 30 Voie Romaine, Nice, France.
Florent PoirierService de NeuroInterventionnel, CHU de Nice Hôpital, Pasteur 2, 30 Voie Romaine, Nice, France.
Modhar JamjoomService de NeuroInterventionnel, CHU de Nice Hôpital, Pasteur 2, 30 Voie Romaine, Nice, France.
Charles RaffaelliService de NeuroInterventionnel, CHU de Nice Hôpital, Pasteur 2, 30 Voie Romaine, Nice, France.
Frederic ColombHôpital de Grasse. Chemin de Clavary, Service d'urologie, 06130, Grasse, France.
Yves ChauService de NeuroInterventionnel, CHU de Nice, Hôpital, Pasteur 2, 30 Voie Romaine, Nice, France.
Centre Hospitalier Universitaire de Nice · FRHôpital de La Grave · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study evaluated nontarget embolization (NTE) during prostatic artery embolization (PAE) with ethylene vinyl alcohol copolymer (EVOH).

resultsTen consecutive patients treated by PAE with EVOH for the presence of disabling benign prostatic hyperplasia (BPH)-related lower urinary tract symptoms (LUTS) between June 22 and January 2023 were included in this prospective study. The inclusion criteria were as follows: LUTS attributed to BPH, LUTS duration ≥ 6 months, failure to respond to standard pharmacotherapy, IPSS > 18 or QoL score > 2, and prostate volume > 40 mL. Embolization was performed under general anaesthesia. According to established techniques, a microcatheter was positioned bilaterally within the feeding arteries, and EVOH was injected slowly under X-ray control. Unenhanced pelvic computed tomography scans were carried out before and after embolization to assess the NTE. The safety of the prostatic embolization procedure with EVOH was assessed by collecting adverse effects over 3 months of evaluation that included the International Prostate Symptom Score (IPSS) and quality of life (QoL) score.-up evaluations, occurring at 3, 6, and 12months, included International Prostate Symptom Score. Bilateral PAE was technically successful in 9 patients, and unilateral injection was performed in one patient. The postoperative scanner showed a distribution of the embolization material in the two lobes of the prostate in all patients. The procedure time varied from 120 to 150 (mean: 132) minutes. Eight out of 10 patients developed pollakiuria within 24 h; none of the patients had postoperative pain. Two patients required catheterization for postoperative urinary retention. Catheters were removed successfully at the end of the first day for one of these patients and on the tenth day for the other. At the 3-month follow-up, patients showed significant improvement in the International Prostate Symptom Score (n = 10; mean = -11,5; P < 0.01) and quality of life score (n = 10; mean = -3,40; P < 0.01). Only one patient presented one asymptomatic muscular NTE.

conclusionsPAE with EVOH is safe, effective, and associated with few NTEs and no postoperative pain. Prospective comparative studies with longer follow-ups are warranted.

trial registrationIDRCB, 2021-AO29-56-35. Registered 27 May 2022, http://clinicaltrials.gov/study/NCT05395299?cond=embolization&term&rank=1 .

Indexed as

Benign prostate hyperplasiaEthylene vinyl alcohol copolymerLower urinary tract symptomsProstate artery embolization

Identifiers

PMID37922055
PMCPMC10624789
OpenAlexW4388303472

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.