Evidence map›Paper›PMID 37921967›Full record

ArticleJournal of occupational rehabilitation2024

Work Difficulties in People with Multiple Sclerosis.

Michela Ponzio, Jessica Podda, Elena Pignattelli, Anna Verri, Benedetta Persechino, Bruno Kusznir Vitturi, Paolo Bandiera, Tommaso Manacorda, Matilde Inglese, Paolo Durando and 1 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of occupational rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06805318 (Development and Assessment of a Vocational Rehabilitation Intervention for Job Retention in Workers With Multiple Sclerosis), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06805318 narecruitingnot on this mapstarted 2025, after this paper: background citation

Development and Assessment of a Vocational Rehabilitation Intervention for Job Retention in Workers With Multiple Sclerosis (RiaLSM Intervention Project)

TypeinterventionalSponsorFondazione Italiana Sclerosi MultiplaRan2025 to 2025Enrolled30ConditionsMultiple Sclerosis, Vocational RehabilitationArmsVocational Rehabilitation intervention for pwMS
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  9. Identifying key determinants of work-related difficulties in multiple sclerosis: integrating clinical measures and socio-occupational factors.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Michela PonzioScientific Research Area, Italian Multiple Sclerosis Foundation (FISM), Genoa, Italy. michela.ponzio@aism.it.ORCID 0000-0001-5245-0474
Jessica PoddaScientific Research Area, Italian Multiple Sclerosis Foundation (FISM), Genoa, Italy.
Elena PignattelliScientific Research Area, Italian Multiple Sclerosis Foundation (FISM), Genoa, Italy.
Anna VerriScientific Research Area, Italian Multiple Sclerosis Foundation (FISM), Genoa, Italy.
Benedetta PersechinoItalian Workers' Compensation Authority (INAIL), Rome, Italy.
Bruno Kusznir VitturiDepartment of Health Sciences, University of Genoa, Genoa, Italy.
Paolo BandieraItalian Multiple Sclerosis Association (AISM), Genoa, Italy.
Tommaso ManacordaItalian Multiple Sclerosis Association (AISM), Genoa, Italy.
Matilde IngleseDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), Center of Excellence for Biomedical Research (CEBR), University of Genoa, Genoa, Italy.
Paolo DurandoDepartment of Health Sciences, University of Genoa, Genoa, Italy.
Mario Alberto BattagliaScientific Research Area, Italian Multiple Sclerosis Foundation (FISM), Genoa, Italy.
Associazione Italiana Sclerosi Multipla · ITUniversity of Genoa · ITIstituto Nazionale per l'Assicurazione Contro gli Infortuni sul Lavoro · ITMultiple Sclerosis Foundation · USOspedale Policlinico San Martino · ITUniversity of Siena · IT

Funding

Italian Workers' Compensation Authority (INAIL) Bando BRIC 2019_ID 24
6 · The paper itself

Abstract

purposeThis study identifies potential predictors of unemployment and describes specific work difficulties and their determinants in a subgroup of employed people with multiple sclerosis (PwMS). The specific work difficulties were evaluated using a validated tool that measures the impact of respondents' symptoms and of workplace features.

methodsA cross-sectional study was carried out in Italy during 2021-2022. The subjects included were adults (18-65 years) with a diagnosis of MS, currently employed or unemployed. Logistic regression models were used to determine the association between each potential determinant and employment status, while linear regression models were used to determine the association between determinants and specific work difficulties.

resultsThe main risk factors associated with a higher risk of being unemployed were being older, living in the South of Italy/islands, and having a higher disability level, while protective factors against unemployment were having a high level of education and 'stable' employment (an open-ended contract). Fatigue was found to be associated with all work difficulties analyzed; mood disorders emerged as the main predictors of mental health-related work difficulties; level of disability and comorbidity significantly impacted physical health-related ones, and a good quality of life was found to improve both workplace-related and mental health-related difficulties at work.

conclusionIdentifying the most significant difficulties is a crucial step in the development of vocational rehabilitation interventions tailored to maximize the ability of PwMS to handle their job-related duties and demands.

Indexed as

EmploymentMultiple SclerosisUnemploymentAdolescentAdultAgedCross-Sectional StudiesFatigueFemaleHumansItalyMaleMiddle AgedMood DisordersQuality of LifeRisk FactorsDisabilityEmploymentMultiple sclerosisWork difficulties

Identifiers

PMID37921967
PMCPMC11364583
OpenAlexW4388304293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.