Evidence map›Paper›PMID 37921790›Full record

Trial reportJACC. Clinical electrophysiology2024

Preceding Night Sleep Quality and Atrial Fibrillation Episodes in the I-STOP-AFIB Randomized Trial.

Christopher X Wong, Madelaine Faulkner Modrow, Kathi Sigona, Janet J Tang, Eric Vittinghoff, Mellanie True Hills, Debbe McCall, Kathleen Sciarappa, Mark J Pletcher, Jeffrey E Olgin and 1 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in JACC. Clinical electrophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Sleep-Disordered Breathing and Cardiac Arrhythmias.Journal of clinical medicine · 2024
    Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Christopher X WongDivision of Cardiology, University of California-San Francisco, San Francisco, California, USA.
Madelaine Faulkner ModrowDepartment of Epidemiology and Biostatistics, University of California-San Francisco, San Francisco, California.
Kathi SigonaHealth eHeart Alliance, Washington, DC, USA.
Janet J TangDivision of Cardiology, University of California-San Francisco, San Francisco, California, USA.
Eric VittinghoffDepartment of Epidemiology and Biostatistics, University of California-San Francisco, San Francisco, California.
Mellanie True HillsHealth eHeart Alliance, Washington, DC, USA.
Debbe McCallHealth eHeart Alliance, Washington, DC, USA.
Kathleen SciarappaHealth eHeart Alliance, Washington, DC, USA.
Mark J PletcherDepartment of Epidemiology and Biostatistics, University of California-San Francisco, San Francisco, California.
Jeffrey E OlginDivision of Cardiology, University of California-San Francisco, San Francisco, California, USA.
Gregory M MarcusDivision of Cardiology, University of California-San Francisco, San Francisco, California, USA. Electronic address: greg.marcus@ucsf.edu.
University of California, San Francisco · US

Funding

The Health ePeople Resource for Mobilized ResearchU2CEB021881 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARCUS, GREGORY M, OLGIN, JEFFREY E · 2015 to 2020
$10.3M
NIBIB NIH HHS U2C EB021881
6 · The paper itself

Abstract

backgroundChronic sleep disruption is associated with incident atrial fibrillation (AF), but it is unclear whether poor sleep quality acutely triggers AF.

objectivesThe aim of this study was to characterize the relationship between a given night's sleep quality and the risk of a discrete AF episode.

methodsPatients with symptomatic paroxysmal AF in the I-STOP-AFIB (Individualized Studies of Triggers of Paroxysmal Atrial Fibrillation) trial reported sleep quality on a daily basis. Participants were also queried daily regarding AF episodes and were provided smartphone-based mobile electrocardiograms (ECGs) (KardiaMobile, AliveCor).

resultsUsing 15,755 days of data from 419 patients, worse sleep quality on any given night was associated with a 15% greater odds of a self-reported AF episode the next day (OR: 1.15; 95% CI: 1.10-1.20; P < 0.0001) after adjustment for the day of the week. No statistically significant associations between worsening sleep quality and mobile ECG-confirmed AF events were observed (OR: 1.04; 95% CI: 0.95-1.13; P = 0.43), although substantially fewer of these mobile ECG-confirmed events may have limited statistical power. Poor sleep was also associated with longer self-reported AF episodes, with each progressive category of worsening sleep associated with 16 (95% CI: 12-21; P < 0.001) more minutes of AF the next day.

conclusionsPoor sleep was associated with an immediately heightened risk for self-reported AF episodes, and a dose-response relationship existed such that progressively worse sleep was associated with longer episodes of AF the next day. These data suggest that sleep quality may be a potentially modifiable trigger relevant to the near-term risk of a discrete AF episode.

Indexed as

Atrial FibrillationElectrocardiographyHumansSleep Qualityatrial fibrillationdigitalsleepsmartphonetriggers

Identifiers

PMID37921790
OpenAlexW4388125608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.