Evidence map›Paper›PMID 37921662›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2024

Preeclampsia-exposed children's heart rate variability 8-12 yr after index pregnancy: FINNCARE study.

Michelle Renlund, Mikko P Tulppo, Anni Kivelä, Hannele Laivuori, Seppo Heinonen, Tiina Jääskeläinen, Taisto Sarkola

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Michelle RenlundChildren's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0002-4573-3748
Mikko P TulppoResearch Unit of Biomedicine and Internal Medicine, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
Anni KiveläMedical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0002-4979-998X
Hannele LaivuoriMedical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0003-3212-7826
Seppo HeinonenDepartment of Obstetrics and Gynecology, Helsinki University Hospital, Helsinki, Finland.
Tiina JääskeläinenMedical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Taisto SarkolaChildren's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0002-2590-3279
Helsinki University Hospital · FIUniversity of Helsinki · FIOulu University Hospital · FI

Funding

Academy of Finland (AKA)Competitive state research funding of the expert responsibility area of the Helsinki and Uusimaa HospitalCompetitive state research funding of the expert responsibility area of the Tampere University HospitalFinnish Foundation for Pediatric ResearchJane and Aatos Erkko FoundationJuho Vainio FoundationMedicinska stiftelsen i VasaMedicinska Understödsföreningen Liv och Hälsa (Medicinska Understödsföreningen Liv och Hälsa r.f.)Paivikki and Sakari Sohlberg FoundationSigrid Juselius FoundationStiftelsen Dorothea Olivia, Karl Walter och Jarl Walter Perkléns Minne (Dorothea Olivia, Karl Walter och Jarl Walter Perkléns Foundation)The Medical Society of Finland
6 · The paper itself

Abstract

Preeclampsia is related with elevated systolic blood pressure (SBP) in children. We studied if preeclampsia-exposed (PE) children develop alterations in heart rate variability (HRV) and if this is reflected in their blood pressure (BP), as well as overall associations with body size and composition, gestational and perinatal factors. We examined 182 PE (46 early-onset PE) and 85 unexposed (non-PE) children 8-12 yr after preeclampsia exposure. HRV monitoring was performed 5 min in supine followed by 5 min in standing position and compared with office, 24-h ambulatory, and central BPs in relation to body anthropometrics and composition, gestational, and perinatal data. There were no major differences in HRV between PE and non-PE children. HRV in supine position was strongly associated with office and ambulatory heart rates (HRs), and HR was independently associated with office BPs. However, HRV was not related with office or 24-h SBP and PP, nor with elevated SBP in PE compared with non-PE children [adjusted mean differences for office and 24-h SBP 4.8 (

Indexed as

Pre-EclampsiaAutonomic Nervous SystemBlood PressureChildFemaleHeartHeart RateHumansPregnancyadiposityblood pressurecardiovascular diseaseheart rate variabilitypreeclampsia

Identifiers

PMID37921662
PMCPMC11213471
OpenAlexW4388288951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.