Evidence map›Paper›PMID 37921620›Full record

ArticleParasite (Paris, France)2023

Intranasal immunisation with recombinant Toxoplasma gondii uridine phosphorylase confers resistance against acute toxoplasmosis in mice.

Li-Tian Yin, Ying-Jie Ren, Yu-Jie You, Yong Yang, Zhi-Xin Wang, Hai-Long Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasite (Paris, France), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Li-Tian YinKey Laboratory of Cellular Physiology, Ministry of Education, Department of Physiology, Shanxi Medical University, Taiyuan, 030001 Shanxi, China.
Ying-Jie RenSchool of Basic Medicine, Basic Medical Sciences Center, Shanxi Medical University, Jinzhong, Shanxi 030600, China.
Yu-Jie YouSchool of Basic Medicine, Basic Medical Sciences Center, Shanxi Medical University, Jinzhong, Shanxi 030600, China.
Yong YangSchool of Basic Medicine, Basic Medical Sciences Center, Shanxi Medical University, Jinzhong, Shanxi 030600, China.
Zhi-Xin WangSchool of Basic Medicine, Basic Medical Sciences Center, Shanxi Medical University, Jinzhong, Shanxi 030600, China.
Hai-Long WangSchool of Basic Medicine, Basic Medical Sciences Center, Shanxi Medical University, Jinzhong, Shanxi 030600, China.
Shanxi Medical University · CN

Funding

the Fund for Shanxi "1331" Project Quality and Efficiency Improvement Plan 1331KFCthe Natural Science Fund of Shanxi Province 20210302123297
6 · The paper itself

Abstract

Toxoplasmosis is caused by Toxoplasma gondii, which infects all warm-blooded animals, including humans. Currently, control measures for T. gondii infection are insufficient due to the lack of effective medications or vaccines. In this paper, recombinant T. gondii uridine phosphorylase (rTgUPase) was expressed in Escherichia coli and purified via Ni

Indexed as

Protozoan VaccinesToxoplasmaToxoplasmosisToxoplasmosis, AnimalAnimalsAntibodies, ProtozoanCytokinesFemaleHumansImmunizationImmunoglobulin GMiceMice, Inbred BALB CProtozoan ProteinsUridine PhosphorylaseAntibodies, ProtozoanCytokinesImmunoglobulin GProtozoan ProteinsProtozoan VaccinesUridine PhosphorylaseIntranasal immunisationMucosal vaccineRecombination proteinToxoplasma gondiiUridine phosphorylase

Identifiers

PMID37921620
PMCPMC10624161
OpenAlexW4388302688

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.