SynthesisEuropean stroke journal2024
Association between blood pressure variability and outcomes after endovascular thrombectomy for acute ischemic stroke: An individual patient data meta-analysis.
Synthesis in European stroke journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- 2025 update to European Stroke Organisation (ESO) guideline on blood pressure management in acute ischaemic stroke and intracerebral haemorrhage.European stroke journal · 2026Guideline
- Systolic blood pressure within 24 hours after successful reperfusion correlates with outcomes in acute ischemic stroke: a secondary analysis of the EHCHANTED2/MT Trial.Journal of neurointerventional surgery · 2026Trial
- Blood pressure management based on infarct volume after successful endovascular thrombectomy.European stroke journal · 2025Trial
- Article
- Hypotension Requiring Vasopressor Support After Endovascular Thrombectomy: Predictors and Neurological Consequences.Journal of clinical medicine · 2026Article
- Blood Pressure Variability in Acute Ischemic Stroke: Current Evidence, Measurement Challenges, and Future Directions.Journal of clinical hypertension (Greenwich, Conn.) · 2026Review
- Risk factors and predictive model for futile recanalization after mechanical thrombectomy in patients with acute ischemic stroke: A multicenter retrospective study.The Journal of international medical research · 2026Article
- Blood pressure management in patients receiving rescue stenting after failed endovascular treatment in large vessel occlusion acute ischaemic stroke: a multicentre registry.European stroke journal · 2026Article
- Variability in Key Physiological Parameters in Neurocritical Stroke Patients: A Multicenter Observational Study.Journal of clinical medicine · 2026Article
- BP-METROLOGY: non-invasive continuous blood pressure monitoring to predict haemorrhagic transformation after endovascular thrombectomy.European stroke journal · 2026Article
- Blood pressure variability and parenchymal hematoma after endovascular thrombectomy: effect modification by recanalization status and cerebral small vessel disease burden.Frontiers in neurology · 2026Article
- Blood Pressure Management Pre- and Post-Reperfusion in Acute Ischemic Stroke: Evidence and Insights from Recent Studies.Current neurology and neuroscience reports · 2025Review
- Association Between Early Spontaneous Post-Thrombectomy Blood Pressure Reduction and Clinical Outcomes in Large Vessel Occlusion Stroke.Brain and behavior · 2025Article
- Mediation of Time-Related Blood Pressure Variability on Intensive Blood Pressure Lowering and Functional Outcomes Post Endovascular Therapy: A Post Hoc Analysis of the OPTIMAL-BP Trial.Journal of the American Heart Association · 2025Article
- Association of hemodynamic variability during endovascular stroke treatment with functional outcome and parenchymal hemorrhage.Therapeutic advances in neurological disorders · 2025Article
- Blood pressure variability in acute stroke: Risk factors and association with functional outcomes at 1 month.European journal of neurology · 2024Article
- Blood pressure management after endovascular thrombectomy: Insights of recent randomized controlled trials.CNS neuroscience & therapeutics · 2024Review
- Blood Pressure Variability in Acute Stroke: A Narrative Review.Journal of clinical medicine · 2024Review
- Correlation between blood pressure variability and prognosis of endovascular therapy in ischemic stroke due to middle cerebral artery occlusion.Frontiers in neurologyArticle
- Mean systolic blood pressure upon admission and clinical outcomes after endovascular treatment in patients with large vessel occlusion beyond 24 hours.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
26 authors.
Funding
Abstract
introductionData on the association between blood pressure variability (BPV) after endovascular thrombectomy (EVT) for acute ischemic stroke (AIS) and outcomes are limited. We sought to identify whether BPV within the first 24 hours post EVT was associated with key stroke outcomes.
methodsWe combined individual patient-data from five studies among AIS-patients who underwent EVT, that provided individual BP measurements after the end of the procedure. BPV was estimated as either systolic-BP (SBP) standard deviation (SD) or coefficient of variation (CV) over 24 h post-EVT. We used a logistic mixed-effects model to estimate the association [expressed as adjusted odds ratios (aOR)] between tertiles of BPV and outcomes of 90-day mortality, 90-day death or disability [modified Rankin Scale-score (mRS) > 2], 90-day functional impairment (⩾1-point increase across all mRS-scores), and symptomatic intracranial hemorrhage (sICH), adjusting for age, sex, stroke severity, co-morbidities, pretreatment with intravenous thrombolysis, successful recanalization, and mean SBP and diastolic-BP levels within the first 24 hours post EVT.
resultsThere were 2640 AIS-patients included in the analysis. The highest tertile of SBP-SD was associated with higher 90-day mortality (aOR:1.44;95% CI:1.08-1.92), 90-day death or disability (aOR:1.49;95% CI:1.18-1.89), and 90-day functional impairment (adjusted common OR:1.42;95% CI:1.18-1.72), but not with sICH (aOR:1.22;95% CI:0.76-1.98). Similarly, the highest tertile of SBP-CV was associated with higher 90-day mortality (aOR:1.33;95% CI:1.01-1.74), 90-day death or disability (aOR:1.50;95% CI:1.19-1.89), and 90-day functional impairment (adjusted common OR:1.38;95% CI:1.15-1.65), but not with sICH (aOR:1.33;95% CI:0.83-2.14).
conclusionsBPV after EVT appears to be associated with higher mortality and disability, independently of mean BP levels within the first 24 h post EVT. BPV in the first 24 h may be a novel target to improve outcomes after EVT for AIS.
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