Evidence map›Paper›PMID 37921040›Full record

ArticleJournal of global health2023

Visual impairment and blindness caused by retinal diseases: A nationwide register-based study.

Chuandi Zhou, Shu Li, Luyao Ye, Chong Chen, Shu Liu, Hongxia Yang, Peng Zhuang, Zengye Liu, Hongwen Jiang, Jing Han and 50 more

Open access · goldAbstract read
In one paragraph

Article in Journal of global health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

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  14. ROQUS: a retinal OCT quality and usability score.Biomedical optics express · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

60 authors at 20 institutions in 2 countries.

Chuandi Zhou *Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai, China.
Shu Li *Department of Nursing, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Luyao Ye *Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai, China.
Chong ChenDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai, China.
Shu LiuDepartment of Ophthalmology, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong Province, China.
Hongxia YangDepartment of Ophthalmology, The First People's Hospital of Jinzhong, Jinzhong, Liaoning Province, China.
Peng ZhuangDepartment of Ophthalmology, Zhangzhou Municipal Hospital of Fujian Province, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian Province, China.
Zengye LiuDepartment of Ophthalmology, Tianjin First Central Hospital, Tianjin, China.
Hongwen JiangDepartment of Ophthalmology, The First People's Hospital of Kashgar, Kashgar, Xinjiang Uighur Autonomous Region, China.
Jing HanDepartment of Ophthalmology, The Second Affiliated Hospital of Air Force Medical University, Xi'an, Shanxi Province, China.
Yiping JiangDepartment of Ophthalmology, The First Affiliated Hospital of Gannan Medical University, Gannan, Jiangxi Province, China.
Liqin ZhouDepartment of Ophthalmology, The First Hospital of Jiaxing, Affiliatd Hospital of Jiaxing University, Jiaxing, Zhejiang Province, China.
Xiyuan ZhouDepartment of Ophthalmology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jun XiaoDepartment of Ophthalmology, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Cangxia ZhangDepartment of Ophthalmology, Cangzhou Hospital of Integrated TCM-WM of Hebei, Cangzhou, Hebei Province, China.
Lihui WenDepartment of Ophthalmology, The Second People's Hospital of Guilin, Guilin, Guangxi Province, China.
Changjun LanDepartment of Ophthalmology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan Province, China.
Yuqing WangDepartment of Ophthalmology, The First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang Province, China.
Tao SunDepartment of Ophthalmology, Yancheng City No. 1 People's Hospital, Yancheng, Jiangsu Province, China.
Li JiangDepartment of Ophthalmology, Benxi Central Hospital, Benxi, Liaoning Province, China.
Peipei XieDepartment of Ophthalmology, The 152th Central Hospital of the People's Liberation Army, Pingdingshan, Henan Province, China.
Fan ChenDepartment of Ophthalmology, Anqing Municipal Hospital, Anqing, Anhui Province, China.
Ge LiangDepartment of Ophthalmology, PLA Rocket Force Characteristic Medical Center, Beijing, China.
Dongdong FuDepartment of Ophthalmology, People's Hospital of Zunyi City Bo Zhou District, Zunyi, Guzhou Province, China.
Tianzi ZhangDepartment of Ophthalmology, Affiliated Hospital of Inner Mongolia Minzu University, Tongliao, Inner Mongolia Autonomous Region, China.
Xuetao ShiDepartment of Ophthalmology, Pu'er City People's Hospital, Pu'er, Yunnan Province, China.
Zhengyu SongDepartment of Ophthalmology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xinghong LiuDepartment of Ophthalmology, The Central Hospital of Shaoyang, Shaoyang, Hunan Province, China.
Shanshan LiDepartment of Ophthalmology, Workers' Hospital of Jinchuan Group Co., Ltd, Jinchang, Gansu Province, China.
Pengcheng LiDepartment of Ophthalmology, Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Xiangzhou XuDepartment of Ophthalmology, Huizhou First Hospital, Huizhou, Guangdong Province, China.
Qinfeng WeiDepartment of Ophthalmology, The Second People's Hospital of Xining, Xining, Qinghai Province, China.
Weibang WangDepartment of Ophthalmology, The First People's Hospital of Yinchuan, The Second Affiliated Hospital of Ningxia Medical School, Yinchuan, Ningxia Hui autonomous region, China.
Xionggao HuangDepartment of Ophthalmology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China.
Zhen DeDepartment of Ophthalmology, Shigatse People's Hospital, Shigatse, Tibet Autonomous Region, China.
Aijun DengDepartment of Ophthalmology, Affiliated Hospital of Weifang Medical School, Weifang, Shandong Province, China.
Lin DingDepartment of Ophthalmology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang Uygur Autonomous Region, China.
Xiuhong PanYuncheng Eye Hospital, Yuncheng, Shanxi Province, China.
Haiyan WenDepartment of Ophthalmology, People's Hospital of Jilin City, Jilin, Jilin Province, China.
Zhongchen ZhangDepartment of Ophthalmology, Hebei Yanda Hospital, Langfang, Hebei Province, China.
Hongbin LvDepartment of Ophthalmology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province, China.
Jian ZhangDepartment of Ophthalmology, Shaanxi Provincial People's Hospital, Xi'an, Shanxi Province, China.
Xuemin TianDepartment of Ophthalmology, The 988th Hospital of Joint Logistics Support Force of the Chinese People's Liberation Army, Kaifeng, Henan Province, China.
Zhen DengDepartment of Ophthalmology, The First People's Hospital of Linping District, Hangzhou, Zhejiang Province, China.
Hua WangDepartment of Ophthalmology, The First People's Hospital of Lianyungang, Lianyungang, Jiangsu Province, China.
Fang WangDepartment of Ophthalmology, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou Province, China.
Yu WangFushun Ophthalmopathy Hospital, Fushun, Liaoning Province, China.
Hongchao ZhaoDepartment of Ophthalmology, People's Hospital of Yuxi City, Yuxi, Yunnan Province, China.
Yanhong FangDepartment of Ophthalmology, Jiangjin Central Hospital, Chongqing, China.
Yuyu WuDepartment of Ophthalmology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, China.
Yufeng WuDepartment of Ophthalmology, Qingyang People's Hospital, Qingyang, Gansu Province, China.
Nian ShenDepartment of Ophthalmology, Liuzhou People's Hospital, Liuzhou, Guangxi Zhuang Autonomous Region, China.
Bo LiDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai, China.
Xiaorong LiDepartment of Ophthalmology, Tianjin Medical University Eye Hospital, School of Optometry & Eye Institute, Tianjin, China.
Hong DaiDepartment of Ophthalmology, Beijing Hospital, Beijing, China.
Naiqing ZhaoDepartment of Biostatistics, Fudan University School of Public Health, Shanghai, China.
Xiaodong SunDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai, China.
Zhi ZhengDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai, China.
Kun LiuDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai, China.
Xun XuDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai engineering center for precise diagnosis and treatment of eye diseases, Shanghai, China.
National Clinical Research · USShanghai Eye Disease Prevention & Treatment Center · CNShanghai First People's Hospital · CNHuizhou Central People's Hospital · CNLiaoning Shihua University · CNShanghai Jiao Tong University · CNAffiliated Hospital of North Sichuan Medical College · CNAffiliated Hospital of Southwest Medical University · CNAir Force Medical University · CNAnqing City Hospital · CNBinzhou University · CNChinese People's Liberation Army · CNChongqing Medical University · CNFirst Affiliated Hospital of Gannan Medical University · CNFirst People’s Hospital of Zunyi · CNFudan University · CNFujian Medical University · CNHainan General Hospital · CNHangzhou First People's Hospital · CNHuazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Retinal disorders cause substantial visual burden globally. Accurate estimates of the vision loss due to retinal diseases are pivotal to inform optimal eye health care planning and allocation of medical resources. The purpose of this study is to describe the proportion of visual impairment and blindness caused by major retinal diseases in China. Methods: A nationwide register-based study of vitreoretinal disease covering all 31 provinces (51 treating centres) of mainland China. A total of 28 320 adults diagnosed with retinal diseases were included. Participants underwent standardised ocular examinations, which included best-corrected visual acuity (BCVA), dilated-fundus assessments, and optical coherence tomography. Visual impairment and blindness are defined using BCVA according to the World Health Organization (WHO) (visual impairment: <20/63-≥20/400; blindness: <20/400) and the United States (visual impairment: <20/40-≥20/200; blindness: <20/200) definitions. The risk factors of vision loss were explored by logistic regression analyses. Results: Based on the WHO definitions, the proportions for unilateral visual impairment and blindness were 46% and 18%, respectively, whereas those for bilateral visual impairment and blindness were 31% and 3.3%, respectively. Diabetic retinopathy (DR) accounts for the largest proportion of patients with visual impairment (unilateral visual impairment: 32%, bilateral visual impairment: 60%) and blindness (unilateral blindness: 35%; bilateral blindness: 64%). Other retinal diseases that contributed significantly to vision loss included age-related macular degeneration, myopic maculopathy, retinal vein occlusion, and rhegmatogenous retinal detachment and other macular diseases. Women (bilateral vision loss: P = 0.011), aged patients (unilateral vision loss: 45-64 years: P < 0.001, ≥65 years: P < 0.001; bilateral vision loss: 45-64 years: P = 0.003, ≥65 years: P < 0.001 (reference: 18-44 years)) and those from Midwest China (unilateral and bilateral vision loss: both P < 0.001) were more likely to suffer from vision loss. Conclusions: Retinal disorders cause substantial visual burden among patients with retinal diseases in China. DR, the predominant retinal disease, is accountable for the most prevalent visual disabilities. Better control of diabetes and scaled-up screenings are warranted to prevent DR. Specific attention should be paid to women, aged patients, and less developed regions.

Indexed as

Diabetic RetinopathyMacular DegenerationPersons with Visual DisabilitiesRetinal DiseasesVision, LowAdultAgedBlindnessFemaleHumansPrevalenceVision DisordersVisual Acuity

Identifiers

PMID37921040
PMCPMC10623496
OpenAlexW4388302825

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.