Observational studyThoracic cancer2023
Trajectories and risk factors of persistent cough after pulmonary resection: A prospective two-center study.
Observational study in Thoracic cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07524712 (Preliminary Study on the Associated Mechanisms Between Surgical Instruments and Postoperative Cough), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Preliminary Study on the Associated Mechanisms Between Surgical Instruments and Postoperative Cough
Who cites it
15 citing papers in PubMed, 11 citations in OpenAlex.
- Mixed-Methods User-Centered Design Evaluation of an Electronic Patient-Reported Outcomes System to Enhance Postdischarge Care for Thoracic Surgery Patients.The Journal of surgical research · 2026Article
- Innovative Tools and Perspectives in Cough Management: Cancer and Cough.Tuberculosis and respiratory diseases · 2026Review
- Thoracoscopic Incomplete Anatomical Segmentectomy for Ground-Glass-Dominant Lung Cancer: Associations with Lower Postoperative Cough Burden and Faster Symptom Recovery.Annals of surgical oncology · 2026Article
- Symptom Cluster Trajectories of Cough, Shortness of Breath, and Disturbed Sleep in Patients Undergoing Lung Cancer Surgery: A Longitudinal Study.Annals of surgical oncology · 2026Article
- A retrospective study with whole-exome sequencing of tissue samples: analysis of risk factors in patients of persistent cough following lung segmentectomy.Journal of thoracic disease · 2025Article
- Analysis of the Effectiveness of a Total Management Model in the Management of Chronic Cough After Lung Cancer Surgery.Thoracic cancer · 2025Article
- Establishment and validation of a risk prediction model for postoperative persistent cough in lung resection patients: a systematic review and meta-analysis-based approach.Journal of thoracic disease · 2025Article
- [Effect of Lymph Node Clearance Modalities on Chronic Cough after Surgery in Non-small Cell Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2025Article
- Risk factors for cough after pulmonary resection in patients with non-small cell lung cancer: a systematic review and meta-analysis.Journal of thoracic disease · 2025Article
- Budesonide/glycopyrronium/formoterol fumarate co-suspension metered dose inhaler relieves cough after lobectomy: a randomized controlled study.Translational lung cancer research · 2025Article
- Optical sensor for fast and accurate lung cancer detection with tissue autofluorescence and diffuse reflectance spectroscopy.Thoracic cancer · 2025Article
- Pilot study of incidence of gastroesophageal reflux after lung resection.Journal of thoracic disease · 2024Article
- Review
- Analysis of Influencing Factors and Construction of Predictive Model for Persistent Cough After Lung Cancer Resection Under Thoracoscopy.Therapeutics and clinical risk management · 2024Article
- Trajectories and risk factors of persistent cough after pulmonary resection: A prospective two-center study.Thoracic cancer · 2023Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundPersistent cough is one of the most frequent complications following lung cancer surgery. To promote optimal recovery, we conducted a study to investigate the trajectories of coughing symptoms and their impact on quality of life (QOL), as well as to identify potential risk factors of persistent cough after pulmonary resection (CAP).
methodsThis prospective observational study assessed patients who underwent pulmonary resection for lung tumor at two medical centers in China. Persistent CAP was evaluated before surgery, at discharge, and 1, 3, and 6 months following surgery using visual analog scale (VAS), cough symptom score (CSS), and Leicester Cough Questionnaire in Mandarin Chinese (LCQ-MC). Univariate and multivariate logistic regression analyses were conducted to explore independent risk factors for persistent CAP.
resultsOf the 506 enrolled patients, 130 patients were diagnosed with persistent CAP with an incidence of 25.69%. Compared to the noncough group, patients with persistent CAP reported significantly higher VAS (p < 0.001) and CSS scores (p < 0.001) and experienced worse QOL (p < 0.001) for up to 6 months, particularly at 1 month following surgery. Multivariable regression analysis revealed that a duration of anesthesia exceeding 156 min (odds ratio [OR]: 1.847, 95% confidence interval [CI]: 1.156-2.951, p = 0.010) and gastroesophageal acid reflux (GER) (OR: 3.870, 95% CI: 2.376-6.304, p < 0.001) were independent risk factors of persistent CAP.
conclusionPatients who suffer from persistent CAP face a substantial burden and diminished QOL for an extended period compared to noncough patients. Moreover, prolonged duration of anesthesia and postoperative GER are potential risk factors of persistent CAP.
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Registered trials
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