Evidence map›Paper›PMID 37920897›Full record

ArticleOsong public health and research perspectives2023

Evaluation of COVID-19 vaccine effectiveness in different high-risk facility types during a period of Delta variant dominance in the Republic of Korea: a cross-sectional study.

Min Jei Lee, Myung-Jae Hwang, Dong Seob Kim, Seon Kyeong Park, Jihyun Choi, Ji Joo Lee, Jong Mu Kim, Young-Man Kim, Young-Joon Park, Jin Gwack and 1 more

Abstract read
In one paragraph

Article in Osong public health and research perspectives, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Min Jei LeeCentral Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.
Myung-Jae HwangDivision of Public Health Emergency Response Research, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.
Dong Seob KimGyeonam Regional Center for Disease Control and Prevention, Korea Disease Control and Prevention Agency, Busan, Republic of Korea.
Seon Kyeong ParkGyeonam Regional Center for Disease Control and Prevention, Korea Disease Control and Prevention Agency, Busan, Republic of Korea.
Jihyun ChoiCentral Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.
Ji Joo LeeCentral Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.
Jong Mu KimCentral Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.
Young-Man KimCentral Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.
Young-Joon ParkCentral Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.
Jin GwackDivision of Infectious Disease Control, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.
Sang-Eun LeeCentral Disease Control Headquarters, Korea Disease Control and Prevention Agency, Cheongju, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe evaluated the effectiveness of coronavirus disease 2019 vaccination in high-risk facilities in the Republic of Korea during the period when the highly transmissible Delta variant was prevalent. Additionally, we aimed to explore any disparities in vaccine effectiveness (VE) across various types of institutions, specifically distinguishing between non-medical and medical establishments.

methodsWe examined 8 outbreak clusters covering 243 cases and 895 contacts from 8 high-risk facilities divided into 2 groups: group A (4 non-medical institutions) and group B (4 medical institutions). These clusters were observed from July 27, 2021 to October 16, 2021 for the attack rate (AR) and VE with respect to disease severity. A generalized linear model with a binomial distribution was used to determine the odds ratio (OR) for disease severity and death.

resultsAR was notably lower in group B (medical institutions). Furthermore, VE analysis revealed that group A exhibited higher effectivity for disease severity and death than group B. The OR for disease severity was 0.24 (95% confidence interval [CI], 0.03-2.16) for group A and 0.27 (95% CI, 0.12-0.64) for group B, with the OR for death at 0.12 (95% CI, 0.01-1.32) in group A and 0.34 (95% CI, 0.14-0.87) in group B.

conclusionAlthough VE may vary across institutions, our findings underscore the importance of implementing vaccinations in high-risk facilities. Customized vaccination programs, tailored response plans, and competent management personnel are essential for effectively addressing and mitigating public health challenges.

Indexed as

Communicable diseasesCOVID-19COVID-19 vaccinesSARS-CoV-2Vaccine efficacy

Identifiers

PMID37920897
PMCPMC10626323

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.