Evidence map›Paper›PMID 37920792›Full record

ArticleFrontiers in pediatrics2023

Risk factors for health impairments in children after hospitalization for acute COVID-19 or MIS-C.

Aline B Maddux, Cameron C Young, Suden Kucukak, Laura D Zambrano, Margaret M Newhams, Caitlin K Rollins, Natasha B Halasa, Shira J Gertz, Elizabeth H Mack, Stephanie Schwartz and 23 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Post-MIS-C cardiovascular outcomes: a systematic review.European journal of pediatrics · 2026
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 20 institutions in 1 country.

Aline B MadduxSection of Critical Care Medicine, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, United States.
Cameron C YoungCritical Care, and Pain Medicine, Department of Anesthesiology, Boston Children's Hospital, Boston, MA, United States.
Suden KucukakCritical Care, and Pain Medicine, Department of Anesthesiology, Boston Children's Hospital, Boston, MA, United States.
Laura D ZambranoCOVID-19 Response, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Margaret M NewhamsCritical Care, and Pain Medicine, Department of Anesthesiology, Boston Children's Hospital, Boston, MA, United States.
Caitlin K RollinsDepartments of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, United States.
Natasha B HalasaDivision of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, United States.
Shira J GertzDivision of Pediatric Critical Care, Department of Pediatrics, Cooperman Barnabas Medical Center, Livingston, NJ, United States.
Elizabeth H MackDivision of Pediatric Critical Care Medicine, Medical University of South Carolina, Charleston, SC, United States.
Stephanie SchwartzDepartment of Pediatrics, University of North Carolina at Chapel Hill Children's Hospital, Chapel Hill, NC, United States.
Michele KongDivision of Pediatric Critical Care Medicine, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, United States.
Laura L LoftisSection of Critical Care Medicine, Department of Pediatrics, Texas Children's Hospital, Houston, TX, United States.
Katherine IrbySection of Pediatric Critical Care, Department of Pediatrics, Arkansas Children's Hospital, Little Rock, AR, United States.
Courtney M RowanDivision of Pediatric Critical Care Medicine, Department of Pediatrics, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN, United States.
Keiko M TarquinioDivision of Critical Care Medicine, Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA, United States.
Matt S ZinterDepartment of Pediatrics, Division of Critical Care, University of California San Francisco, San Francisco, CA, United States.
Hillary CrandallDivision of Pediatric Critical Care, Department of Pediatrics, Primary Children's Hospital, University of Utah, Salt Lake City, UT, United States.
Natalie Z CvijanovichDivision of Critical Care Medicine, UCSF Benioff Children's Hospital, Oakland, CA, United States.
Jennifer E SchusterDivision of Pediatric Infectious Disease, Department of Pediatrics, Children's Mercy Kansas City, Kansas City, MO, United States.
Julie C FitzgeraldDepartment of Anesthesiology and Critical Care, Perelman School of Medicine, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States.
Mary A StaatDepartment of Pediatrics, Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, United States.
Charlotte V HobbsDivision of Infectious Diseases, Department of Pediatrics, University of Mississippi Medical Center, Jackson, MS, United States.
Ryan A NofzigerDivision of Critical Care Medicine, Akron Children's Hospital, Akron, OH, United States.
Steven SheinDivision of Pediatric Critical Care Medicine, Rainbow Babies and Children's Hospital, Cleveland, OH, United States.
Heidi FloriDivision of Pediatric Critical Care Medicine, Department of Pediatrics, C. S. Mott Children's Hospital and University of Michigan, Ann Arbor, MI, United States.
Melissa L CullimoreDivision of Pediatric Critical Care, Department of Pediatrics, Children's Hospital and Medical Center, Omaha, NE, United States.
Brandon M ChataniDivision of Pediatric Infectious Disease, Department of Pediatrics, AdventHealth for Children, Orlando, FL, United States.
Emily R LevyDivision of Pediatric Infectious Diseases, Division of Pediatric Critical Care Medicine, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, United States.
Katri V TyppoDiamond Children's Banner Children's Medical Center, University of Arizona, Tucson, AZ, United States.
Janet R HumeDivision of Pediatric Critical Care, University of Minnesota Masonic Children's Hospital, Minneapolis, MN, United States.
Angela P CampbellCOVID-19 Response, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Adrienne G RandolphDepartment of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, United States.
Overcoming COVID-19 Investigators
Boston Children's Hospital · USCenters for Disease Control and Prevention · USAdventHealth for Children · USAkron Children's Hospital · USArkansas Children's Hospital · USBanner - University Medical Center Tucson · USChildren's Healthcare of Atlanta · USChildren's Hospital Colorado · USChildren's Hospital & Medical Center · USChildren's Mercy Hospital · USHarvard University · USIndiana University School of MedicineMayo Clinic in Florida · USMedical University of South Carolina · USPhiladelphia University · USRainbow Babies & Children's Hospital · USSaint Barnabas Medical Center · USTexas Children's Hospital · USUCSF Benioff Children's Hospital · USUniversity of Alabama at Birmingham · US

Funding

Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI Hisashi Umemori · 2021 to 2026
$9.4M
Functional Outcomes after Prolonged Mechanical Ventilation in ChildrenK23HD096018 · NICHD · UNIVERSITY OF COLORADO DENVER · PI MADDUX, ALINE BERNARD · 2019 to 2023
$807k
NICHD NIH HHS K23 HD096018NICHD NIH HHS P50 HD105351
6 · The paper itself

Abstract

Objective: To identify risk factors for persistent impairments after pediatric hospitalization for acute coronavirus disease 2019 (COVID-19) or multisystem inflammatory syndrome in children (MIS-C) during the SARS-CoV-2 pandemic. Methods: Across 25 U.S. Results: Of 232 children with acute COVID-19, 71 (30.6%) had persistent symptoms and 50 (21.6%) had activity impairments at follow-up; for MIS-C ( Discussion: Among patients hospitalized, nearly one in three hospitalized with acute COVID-19 and one in four hospitalized with MIS-C had persistent impairments for ≥2 months post-hospitalization. Persistent impairments were associated with more severe illness and underlying health conditions, identifying populations to target for follow-up.

Indexed as

COVID-19COVID-19 post-intensive care syndromecritical care outcomesMIS-Cmultisystem inflammatory syndrome in childrenpediatricspost-acute COVID-19 syndromeSARS-CoV-2

Identifiers

PMID37920792
PMCPMC10619659
OpenAlexW4387744033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.